A Less Invasive Technique for Correction of Thoracolumbar Sagittal Deformity in Ankylosing Spondylitis

M. Ibrahim, Mohamed El-Meshtawy, M. Shousha, H. Boehm
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Abstract

Background Data: Ankylosing spondylitis (AS) is a chronic inflammatory disease that can severely alter the normal spinal sagittal balance resulting in functional and social disability. Although the traditional open corrective techniques have provided a great radiographic improvement, they are associated with relatively high morbidity and mortality in an already vulnerable patient with several medical comorbidities. Therefore, a new less invasive technique has been developed in an attempt to achieve both radiographic and clinical improvement while minimizing the possible surgical risks of conventional open approaches.Purpose: To present an innovative less invasive technique for management of thoracic and/or lumbar sagittal imbalance in AS and to evaluate the morbidity, clinical results and radiographic correction following the use of this technique.Study design: Retrospective analysis of prospectively collected data.Methods: Between September 2008 and September 2013, 51 patients (43 males and 8 females) with thoracic and/or lumbar sagittal imbalance due to AS were operated upon. Those patients underwent minimally invasive dorso-ventral osteotomy and reconstruction plus posterior percutaneous instrumentation in the same prone position. Sagittal vertical axis (SVA), T1 pelvic angle (TPA), angle of fusion levels (AFL) and chin-brow vertical angle (CBVA) were used to evaluate radiographic outcomes and degree of correction. Clinical outcomes were assessed by Oswestry Disability Index (ODI) and visual analogue scale (VAS).Results: The mean age at operation was 49.02 years. The mean operative time was 419.31 min with a mean blood loss of 698.24 ml. One third of the patients underwent more than one single dorso-ventral osteotomy. All clinical and radiographic parameters (except for PI) showed a statistically significant improvement after surgery (P 30% improvement from the baseline ODI. Moreover, the changes in ODI were significantly related to the changes in SVA, TPA, AFL and CBVA. Dural tear and transient radiculopathy were the most common complications.onclusion: This technique has obvious advantages in reducing blood loss, optimizing correction and reconstruction, facilitating the postoperative course, and providing satisfactory clinical outcomes. We believe that this novel technique, although technically demanding, offers a safe and effective alternative for traditional open surgery in managing thoracic and/or lumbar sagittal imbalance due to AS. (2018ESJ159)
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微创技术矫正强直性脊柱炎胸腰椎矢状位畸形
背景资料:强直性脊柱炎(AS)是一种慢性炎症性疾病,可严重改变正常的脊柱矢状面平衡,导致功能和社会残疾。尽管传统的开放式矫正技术已经提供了很大的放射学改善,但在患有多种医学合并症的本已脆弱的患者中,它们与相对较高的发病率和死亡率有关。因此,开发了一种新的微创技术,试图在最大限度地降低传统开放式入路可能的手术风险的同时,实现放射学和临床的改进。目的:提出一种创新的微创技术来治疗AS患者的胸和/或腰矢状位失衡,并评估使用该技术后的发病率、临床结果和放射学校正。研究设计:对前瞻性收集的数据进行回顾性分析。方法:2008年9月至2013年9月,对51名因AS导致胸部和/或腰部矢状位失衡的患者(43名男性和8名女性)进行了手术治疗。这些患者在相同的俯卧位接受了微创背腹侧截骨术和重建加上后经皮内固定术。矢状垂直轴(SVA)、T1骨盆角(TPA)、融合水平角(AFL)和下巴-眉毛垂直角(CBVA)用于评估放射学结果和矫正程度。采用Oswestry残疾指数(ODI)和视觉模拟量表(VAS)评估临床疗效。结果:手术时平均年龄为49.02岁。平均手术时间419.31分钟,平均失血698.24毫升。三分之一的患者接受了一次以上的背腹侧截骨。手术后,所有临床和放射学参数(PI除外)均显示出统计学上的显著改善(P)ODI较基线改善30%。此外,ODI的变化与SVA、TPA、AFL和CBVA的变化显著相关。硬脑膜撕裂和短暂性神经根病是最常见的并发症标准结果。我们相信,这项新技术虽然技术要求很高,但为传统的开放手术提供了一种安全有效的替代方案,用于治疗AS引起的胸腰椎矢状位失衡。(2018ESJ159)
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