¿Cuál es el fraccionamiento estándar en la irradiación del cáncer de mama?

Abstract

Radiotherapy (RT) after breast-conserving surgery for breast cancer (BC) has been shown to reduce local recurrence rates and mortality. The conventional treatment of postoperative radiotherapy was 50 to 50.4 Gy, administered in 25 to 28 fractions over a period of 5 to 6 weeks. In the last 20 years, there is clinical evidence to consider hypofractionated treatment regimens safe and effective. Moderate hypofractionation, administered over 3 weeks, can be considered the standard of care after conservative surgery or mastectomy, as well as in irradiation of lymph node areas, with similar results regarding local control and survival and with effects on acute and chronic normal tissue. , similar or smaller. Ultrahypofractionated treatment, administered in 5 sessions, for 1 or 5 weeks, is a safe and effective treatment after conservative surgery and mastectomy without reconstruction. Early results have been reported that ultrahypofractionated treatment in 1 week is safe when lymph node areas are irradiated.