{"title":"Research progresson neoadjuvant chemoradiotherapy for locally advanced rectal cancer","authors":"Yiru Wang, Yong Zhang, Tong Wu, Meizhu Shen","doi":"10.3760/CMA.J.ISSN.1004-4221.2020.03.015","DOIUrl":null,"url":null,"abstract":"Preoperative neoadjuvant chemoradiotherapy (NCR) combined with total mesorectal excision (TME) is the standard treatment mode for locally advanced rectal cancer. Compared with postoperative NCR, preoperative NCR increases the tumor down-staging, sphincter-preserving rate and local control rate. Patients who attain pathological complete response (pCR) after preoperative NCR have better prognosis compared with their counterparts. This article reviews the research progress on preoperative NCR in recent years. \n \nKey words: \nRectal neoplasm/radiochemotherapy; Radiochemotherapy, neoadjuvant; Research progress","PeriodicalId":10288,"journal":{"name":"中华放射肿瘤学杂志","volume":"29 1","pages":"225-228"},"PeriodicalIF":0.0000,"publicationDate":"2020-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华放射肿瘤学杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1004-4221.2020.03.015","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Preoperative neoadjuvant chemoradiotherapy (NCR) combined with total mesorectal excision (TME) is the standard treatment mode for locally advanced rectal cancer. Compared with postoperative NCR, preoperative NCR increases the tumor down-staging, sphincter-preserving rate and local control rate. Patients who attain pathological complete response (pCR) after preoperative NCR have better prognosis compared with their counterparts. This article reviews the research progress on preoperative NCR in recent years.
Key words:
Rectal neoplasm/radiochemotherapy; Radiochemotherapy, neoadjuvant; Research progress
期刊介绍：
The Chinese Journal of Radiation Oncology is a national academic journal sponsored by the Chinese Medical Association. It was founded in 1992 and the title was written by Chen Minzhang, the former Minister of Health. Its predecessor was the Chinese Journal of Radiation Oncology, which was founded in 1987. The journal is an authoritative journal in the field of radiation oncology in my country. It focuses on clinical tumor radiotherapy, tumor radiation physics, tumor radiation biology, and thermal therapy. Its main readers are middle and senior clinical doctors and scientific researchers. It is now a monthly journal with a large 16-page format and 80 pages of text. For many years, it has adhered to the principle of combining theory with practice and combining improvement with popularization. It now has columns such as monographs, head and neck tumors (monographs), chest tumors (monographs), abdominal tumors (monographs), physics, technology, biology (monographs), reviews, and investigations and research.
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