Are the Macular and Choroidal Thicknesses Exchange by the Management of Gyrate Atrophy?

Abstract

Purpose: To identify the macular and choroidal thickness exchange of the case with the gyrate atrophy. Methods: This is a case report of an 11-year-old boy complaining with deteriorated vision and with multiple peripheral lesions in his fundus in the setting of gyrate atrophy. Spectral domain optical coherence tomography showed, cystoid macular edema was in his both eyes. Plasma ornithine level was found elevated. According to these data, the patients were diagnosed with gyrate atrophy of the choroid and retina. The patient treated with vitamin B6 (pyridoxine) and an arginine-restricted diet. Results: The macular and choroidal thickness reduced when the patient keep on his diet. After he abandoned the diet, both macular and choroidal thickness became thicker. Conclusions: This report represents the first case which includes monitoring of the macular and choroidal thickness using spectral-domain optical coherence tomography in a gyrate atrophy case.