Innovative therapeutic approach to chemical burns produced by vesicants; an experimental study

IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Journal of Mind and Medical Sciences Pub Date : 2022-10-23 DOI:10.22543/2392-7674.1355
C. A. Secara, O. Cinteză, D. Popescu, C. Popa, Camelia Andreea Hirjeu, O. Voinea, L. Serbanescu, Andreea Pauna, M. Tudosie
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引用次数: 1

Abstract

Vesicants are compounds that cause severe toxic effects on various tissues. Such chemical action causes tissue necrosis, with clinical expression of skin lesions with a burning character and characteristic blisters. Clinical toxic effects of cutaneous vesicles are correlated with the absorbed dose and exposure time. The goals of the study are to evaluate in vitro the skin toxicity produced by the vesicant chemical compound 2-chloroethyl-ethyl sulfide (CEES), to develop a complex antidote formula
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发泡剂化学烧伤的创新治疗方法;实验研究
水泡剂是一种对各种组织产生严重毒性的化合物。这种化学作用会导致组织坏死,临床表现为具有烧伤特征和特征性水疱的皮肤损伤。皮肤囊泡的临床毒性作用与吸收剂量和暴露时间有关。本研究的目的是在体外评估发泡剂化学化合物2-氯乙基-乙基硫醚(CEES)产生的皮肤毒性,以开发一种复杂的解药配方
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来源期刊
Journal of Mind and Medical Sciences
Journal of Mind and Medical Sciences MEDICINE, GENERAL & INTERNAL-
自引率
61.10%
发文量
37
审稿时长
8 weeks
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