C. A. Secara, O. Cinteză, D. Popescu, C. Popa, Camelia Andreea Hirjeu, O. Voinea, L. Serbanescu, Andreea Pauna, M. Tudosie
{"title":"Innovative therapeutic approach to chemical burns produced by vesicants; an experimental study","authors":"C. A. Secara, O. Cinteză, D. Popescu, C. Popa, Camelia Andreea Hirjeu, O. Voinea, L. Serbanescu, Andreea Pauna, M. Tudosie","doi":"10.22543/2392-7674.1355","DOIUrl":null,"url":null,"abstract":"Vesicants are compounds that cause severe toxic effects on various tissues. Such chemical action causes tissue necrosis, with clinical expression of skin lesions with a burning character and characteristic blisters. Clinical toxic effects of cutaneous vesicles are correlated with the absorbed dose and exposure time. The goals of the study are to evaluate in vitro the skin toxicity produced by the vesicant chemical compound 2-chloroethyl-ethyl sulfide (CEES), to develop a complex antidote formula","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.6000,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Mind and Medical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22543/2392-7674.1355","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 1
Abstract
Vesicants are compounds that cause severe toxic effects on various tissues. Such chemical action causes tissue necrosis, with clinical expression of skin lesions with a burning character and characteristic blisters. Clinical toxic effects of cutaneous vesicles are correlated with the absorbed dose and exposure time. The goals of the study are to evaluate in vitro the skin toxicity produced by the vesicant chemical compound 2-chloroethyl-ethyl sulfide (CEES), to develop a complex antidote formula