Dental concerns of children with lip cleft and palate - a review

S. Nirmala, Degala Saikrishna
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引用次数: 5

Abstract

These are the most severe of congenital anomalies which affect the mouth and related structures. There are one of the most common congenital defects and occur about once in 1000 births. 1 There is a family history in only about one third of cases. Clefts of the palate only are more common in girls while clefts of the lip, with or without palatal involvement, are more common in boys. It is interesting to know that the left side is more often than the right.2 The exact cause of clefting is unknown in most cases. For most cleft conditions, no single factor can be identified as the cause. However, it is important to distinguish between isolated clefts (in which the patient has no other related health problems) and clefts associated with other birth disorders or syndromes.3,4 In the absence of the family history the occurrence of a congenital abnormality may be due to the action of mutation or some chance occurrence during the pregnancy. The lips and palate develop during the 5 -8 weeks of intrauterine life and any factor disrupting the heir formation must exert its influence during this relatively short period. In this respect it is difficult to offer positive views on factors related to maternal health during the pregnancy. it is accepted that German measles and x-ray examination during early pregnancy may produce congenital abnormalities and are to be avoided. The teratogenic action of certain drugs, particularly thalidomide is well known. Infarct the expectant mother is well advised to avoid all necessary drugs taking during the early stages of pregnancy.5-7 (Table 1-3) A useful classification of clefts is that of Kernahan and stark which is bases on an embryological considerations of the tissues involved there are essentially three main groups.7,8
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唇腭裂儿童的牙科问题综述
这些是影响口腔和相关结构的最严重的先天性畸形。这是最常见的先天性缺陷之一,大约每1000个新生儿中就有一个出现。1只有大约三分之一的病例有家族史。腭裂只在女孩中更常见,而唇腭裂,无论是否涉及腭,在男孩中更常见。有趣的是,左侧比右侧更常见。2在大多数情况下,劈开的确切原因尚不清楚。对于大多数裂隙情况,没有单一因素可以确定为原因。然而,重要的是要区分孤立的腭裂(患者没有其他相关的健康问题)和与其他出生障碍或综合征相关的腭裂。3,4在没有家族史的情况下,先天性异常的发生可能是由于突变的作用或妊娠期间的一些偶然发生。唇和腭在子宫内生命的5-8周内发育,任何干扰继承人形成的因素都必须在这段相对较短的时间内发挥作用。在这方面,很难对妊娠期间与产妇健康有关的因素提出积极的看法。人们普遍认为,德国麻疹和早孕期的x光检查可能会产生先天性异常,应避免。某些药物,特别是沙利度胺的致畸作用是众所周知的。梗塞建议孕妇在怀孕早期避免服用所有必要的药物。5-7(表1-3)一种有用的裂隙分类是Kernahan和stark,这是基于对所涉及组织的胚胎学考虑,主要有三类。7,8
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