Influencers of Health Related Quality of Life in People with Faecal Incontinence

Inat Stephanie L, Gill Tiffany K, Avery Jodie C
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Abstract

Background: Faecal Incontinence (FI) is a common debilitating condition that, significantly decreases healthrelated quality of life (HRQoL). However, there is uncertainty about its prevalence and the factors that modulate the relationship between FI and HRQoL, which reduces the efficiency and effectiveness of clinical and public-health interventions. Objective: To assess the prevalence of FI, its risk factors, and determine which factors influence the FI HRQoL relationship. Design: Data was taken from the 2004 representative cross-sectional population South Australian Health Omnibus, n = 3015 men and women aged 15 and over. The main outcome measures were the prevalence and severity of FI, urinary incontinence (UI), other comorbidities and various demographic variables. The SF-36v2 Quality of Life questionnaire was also administered. Results: Prevalence of FI was found to be 1.7% (95% CI: 1.3-2.2%). Univariate analysis found increased reporting in females, those aged 55 and over, separated/divorced, with annual household income < $A30,000 and economically inactive, to be associated with increased reporting. Comorbid UI, depression and obesity also conferred greater risk. HRQoL was decreased in FI compared to those without. Respondents aged over 55 years, being economically inactive and having comorbid depression were associated with significantly more negative HRQoL scores (p < 0.05). Severity of symptoms, gender, annual income and comorbid UI were not associated with any significant difference in HRQoL. Nor were marital status, education status, country of birth, area of residence, comorbid diabetes or Body Mass Index. Conclusions: FI results in a decreased HRQoL, most extreme with increased age, unemployment and those with comorbid depression. Future research is needed to further explore and validate these relationships in order to guide public health interventions and resource allocation.
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粪便失禁患者健康相关生活质量的影响因素
背景:粪便失禁(FI)是一种常见的使人衰弱的疾病,会显著降低与健康相关的生活质量(HRQoL)。然而,其流行率以及调节FI和HRQoL之间关系的因素存在不确定性,这降低了临床和公共卫生干预的效率和有效性。目的:评估FI的患病率及其危险因素,并确定哪些因素影响FI与HRQoL的关系。设计:数据取自2004年具有代表性的南澳大利亚州健康综合人群,n=3015名15岁及以上的男性和女性。主要的结果指标是FI的患病率和严重程度、尿失禁(UI)、其他合并症和各种人口统计学变量。还进行了SF-36v2生活质量问卷调查。结果:FI的患病率为1.7%(95%CI:1.3-2.2%)。单变量分析发现,55岁及以上、分居/离婚、家庭年收入<30000美元且不从事经济活动的女性报告增加与报告增加有关。合并症UI、抑郁症和肥胖也带来了更大的风险。FI组的HRQoL较无FI组降低。年龄在55岁以上、不从事经济活动和患有抑郁症的受访者的HRQoL负评分显著增加(p<0.05)。症状严重程度、性别、年收入和合并症UI与HRQoL的任何显著差异无关。婚姻状况、教育状况、出生国、居住地区、合并糖尿病或体重指数也没有。结论:FI导致HRQoL降低,随着年龄、失业率和合并抑郁症患者的增加,HRQoL下降最为严重。未来的研究需要进一步探索和验证这些关系,以指导公共卫生干预和资源分配。
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