Ceftriaxone-Induced Thrombocytopenia in a Patient with Bacterial Meningoencephalitis

IF 0.4 Q4 PHARMACOLOGY & PHARMACY Journal of Pharmacology & Pharmacotherapeutics Pub Date : 2021-10-01 DOI:10.4103/jpp.jpp_106_21
Anjaly S Kumar, V. Vijay, M. Arya, P. Vasant, S. Chandra, Abhishek Menon
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Abstract

Drug-induced thrombocytopenia is a rare and life-threatening condition. It is mainly caused by the initiation of drug-dependent platelet reactive antibodies that leads to the accelerated platelet destruction. Ceftriaxone is a third-generation cephalosporin, which has rarely reported cases of drug-induced immune thrombocytopenia. Here, we report a case of ceftriaxone-induced thrombocytopenia after the initiation of antibiotic therapy for bacterial meningoencephalitis based on the laboratory findings with the initiation and discontinuation of ceftriaxone.
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头孢曲松致细菌性脑膜脑炎患者血小板减少1例
药物诱导的血小板减少症是一种罕见且危及生命的疾病。它主要是由药物依赖性血小板反应性抗体的引发引起的,该抗体导致血小板加速破坏。头孢曲松是第三代头孢菌素,很少报道药物诱导的免疫性血小板减少症。在此,我们报告了一例在开始和停止使用头孢曲松的实验室结果基础上,开始抗生素治疗细菌性脑膜脑炎后,头孢曲松诱导的血小板减少症。
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