{"title":"The impact of prescriber experience and continuity on adverse drug reactions in hospitalized cancer patients","authors":"Yue Tang, Jingui Xie, Aizong Shen, Lin-Lin Liu, Fei Zhai, Changfang Fu","doi":"10.1080/24725579.2021.1955777","DOIUrl":null,"url":null,"abstract":"Abstract Cancer patients suffer severely from bodily damage due to malignant neoplasms and live a life of low quality, while the occurrence of adverse drug reactions (ADRs) worsens these conditions. Risk factors associated with ADRs have been long discussed in the literature, yet few studies considered prescriber-related risks. This study filled the gap by examining the ADR risk of prescriber-related factors from two dimensions: prescriber experience and prescriber continuity. We conducted a logistic regression analysis to investigate the effects. The data for analysis contained 34,474 inpatient admissions linked to 2,750,685 medication orders. We found that both experienced prescriber and prescriber continuity are related to lower ADR risk. Our results also revealed that the involvement of more experienced physicians in the prescribing process could mitigate the harmful effects of prescriber non-continuity on ADRs.","PeriodicalId":37744,"journal":{"name":"IISE Transactions on Healthcare Systems Engineering","volume":"12 1","pages":"89 - 100"},"PeriodicalIF":1.5000,"publicationDate":"2021-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IISE Transactions on Healthcare Systems Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/24725579.2021.1955777","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract Cancer patients suffer severely from bodily damage due to malignant neoplasms and live a life of low quality, while the occurrence of adverse drug reactions (ADRs) worsens these conditions. Risk factors associated with ADRs have been long discussed in the literature, yet few studies considered prescriber-related risks. This study filled the gap by examining the ADR risk of prescriber-related factors from two dimensions: prescriber experience and prescriber continuity. We conducted a logistic regression analysis to investigate the effects. The data for analysis contained 34,474 inpatient admissions linked to 2,750,685 medication orders. We found that both experienced prescriber and prescriber continuity are related to lower ADR risk. Our results also revealed that the involvement of more experienced physicians in the prescribing process could mitigate the harmful effects of prescriber non-continuity on ADRs.
期刊介绍：
IISE Transactions on Healthcare Systems Engineering aims to foster the healthcare systems community by publishing high quality papers that have a strong methodological focus and direct applicability to healthcare systems. Published quarterly, the journal supports research that explores: · Healthcare Operations Management · Medical Decision Making · Socio-Technical Systems Analysis related to healthcare · Quality Engineering · Healthcare Informatics · Healthcare Policy We are looking forward to accepting submissions that document the development and use of industrial and systems engineering tools and techniques including: · Healthcare operations research · Healthcare statistics · Healthcare information systems · Healthcare work measurement · Human factors/ergonomics applied to healthcare systems Research that explores the integration of these tools and techniques with those from other engineering and medical disciplines are also featured. We encourage the submission of clinical notes, or practice notes, to show the impact of contributions that will be published. We also encourage authors to collect an impact statement from their clinical partners to show the impact of research in the clinical practices.
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