Non-alcoholic fatty liver disease: from understanding risk factors to finding optimal treatment regimens: A review

D. Teplyuk, Aliya A. Kaisina, Shabnam Ibragimova, Af A Bestavashvili, I. O. Tinkova, E. Pashkova, J. Kaibullayeva, A. Nersesov, C. Pavlov
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Abstract

Non-alcoholic fatty liver disease (NAFLD) is now a major risk factor for death among patients with liver disease. Currently, drugs that primarily affect surrogate markers of NAFLD are available. However, none of these drugs showed a significant effect on the course of steatohepatitis and fibrogenesis. The search for the most relevant lifestyle modification programs is still a priority in comprehensive treatment. A clinical case of follow-up of a comorbid patient is presented. Despite comprehensive treatment, disease regression was not achieved. NAFLD therapy remains a relevant issue. Finding new ways to affect the NAFLD course and individualize treatment approaches is necessary.
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非酒精性脂肪肝:从了解危险因素到寻找最佳治疗方案:综述
非酒精性脂肪肝(NAFLD)是肝病患者死亡的主要危险因素。目前,主要影响NAFLD替代标志物的药物是可用的。然而,这些药物都没有显示出对脂肪性肝炎和纤维化过程的显著影响。寻找最相关的生活方式改变方案仍然是综合治疗的优先事项。本文介绍了一例共病患者的临床随访病例。尽管进行了综合治疗,但疾病仍未消退。NAFLD治疗仍然是一个相关问题。寻找新的方法来影响NAFLD的进程和个性化的治疗方法是必要的。
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63
审稿时长
6 weeks
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