Postoperative pulmonary embolism, risk factors, and medical thromboprophylaxis: a 2-year retrospective study

Eman Sobh, Maisa A Abdel Wahab, Zeinab R. Adawy, Heba Abdelgalil, Ola I. Saleh, D. Zakaria, Randa S. Elshahat
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Abstract

Background and aim The major surgical procedures have a significant risk of venous thromboembolism (VTE), especially pulmonary embolism (PE), leading to poor prognosis and life-threatening conditions. The major surgical procedure has 20-fold risk increase in VTE and the risk is increased by 30% in the absence of optimal prophylaxis. This study aimed to estimate the incidence of PE among surgical patients undergoing preoperative thromboprophylaxis according to Caprini score, these considerations can improve the clinical outcome and allow optimal use of thromboprophylactic strategies against VTE. Patients and methods We performed retrospective analysis of records of patients admitted to surgical wards at our hospital and identified those who developed postoperative PE. We calculated Caprini score to assess the risk for VTE. Results Among patients admitted to surgical wards, we identified 107 cases of postoperative PE. Most of them had major surgeries, most of them were females, and a considerable proportion of those who developed PE did not receive thromboprophylaxis although being at moderate or high risk for VTE according to Caprini score. Few patients had poor outcome. Conclusion Perioperative thromboprophylaxis is crucial to avoid complication with VTE. Caprini score may be a good clinical score to decide which patients to receive perioperative thromboprophylaxis.
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术后肺栓塞、危险因素和药物血栓预防:一项2年回顾性研究
背景和目的主要外科手术有发生静脉血栓栓塞(VTE),特别是肺栓塞(PE)的显著风险,导致预后不良和危及生命。主要的外科手术使VTE的风险增加了20倍,在没有最佳预防措施的情况下,风险增加了30%。本研究旨在根据Caprini评分来评估接受术前血栓预防的外科患者中PE的发生率,这些考虑因素可以改善临床结果,并允许针对VTE最佳使用血栓预防策略。患者和方法我们对我院外科病房的患者记录进行了回顾性分析,并确定了术后发生PE的患者。我们计算了Caprini评分来评估VTE的风险。结果在外科病房收治的患者中,我们发现了107例术后PE。他们中的大多数都进行了大手术,其中大多数是女性。根据Caprini评分,尽管VTE的中高风险,但有相当一部分PE患者没有接受血栓预防。很少有患者出现不良结果。结论围手术期血栓预防是避免VTE并发症的关键。Caprini评分可能是一个很好的临床评分,可以决定哪些患者接受围手术期血栓预防。
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审稿时长
34 weeks
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