First Steps in Detection and Interpretation of the Lipid Membrane Boundary Potential

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Abstract

The main stages in the development of electrokinetic studies at the Laboratory of Bioelectrochemistry of the Institute of Physical Chemistry, Russian Academy of Sciences, headed by corr. member of RAS Yu.A. Chizmadzhev, are described. Methods of recording and analyzing the results of measuring the electrophoretic mobility of liposomes using dynamic light scattering techniques are briefly overviewed. The advantage of using electrokinetic data in combination with the measurement of the boundary potentials of planar bilayer lipid membranes using the intramembrane field compensation method has been shown. The data obtained in the framework of this approach is illustrated by studies of effects of some membrane-active ions and compounds on the surface and dipole components of the electric field at the lipid membrane interfaces with an aqueous environment.

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脂膜边界电位检测和解释的第一步
摘要/ abstract摘要:俄罗斯科学院物理化学研究所生物电化学实验室,由俄罗斯科学院院士yuu . a .领导,研究了电动力学研究发展的主要阶段。Chizmadzhev,是描述。简要概述了动态光散射技术测量脂质体电泳迁移率的记录和分析结果的方法。利用电动力学数据结合膜内场补偿法测量平面双层脂质膜的边界电位的优点已经被证明。通过研究一些膜活性离子和化合物对表面的影响以及与水环境的脂膜界面上电场的偶极子成分,可以说明在这种方法框架内获得的数据。
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来源期刊
CiteScore
1.40
自引率
0.00%
发文量
28
期刊介绍: Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology   is an international peer reviewed journal that publishes original articles on physical, chemical, and molecular mechanisms that underlie basic properties of biological membranes and mediate membrane-related cellular functions. The primary topics of the journal are membrane structure, mechanisms of membrane transport, bioenergetics and photobiology, intracellular signaling as well as membrane aspects of cell biology, immunology, and medicine. The journal is multidisciplinary and gives preference to those articles that employ a variety of experimental approaches, basically in biophysics but also in biochemistry, cytology, and molecular biology. The journal publishes articles that strive for unveiling membrane and cellular functions through innovative theoretical models and computer simulations.
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