Selective Attention and Inhibitory Processing in Older Adults: The Impact of Dietary Creatine

Abstract

Aims: The purpose was to examine the relationship between dietary creatine intake obtained in food and selective attention and inhibitory control processes in older adults. Methods: Forty-five (n = 11 males; n = 34 females) participants over 60 years of age volunteered. Participants completed a 5-day dietary recall survey to estimate creatine intake and a cognitive assessment which included an adaptation of the Eriksen flanker task and a mini-mental state examination (MMSE). Cohorts for two groups were derived based on higher (HCr) versus lower (LCr) median creatine intake. To compare the groups, an unpaired Mann-Whitney U test was performed. In addition, Spearman’s correlation analysis was used to test a potential association between the daily amount of creatine with selective attention and inhibitory processing task results. Results: There were significant differences between the groups in the flanker task. In the incongruent condition, HCr responded on average about 646 ms faster than LCr (p = .005). HCr also responded about 25% more accurately than LCr in the incongruent condition (p < .001). Response time to incongruent stimuli (Spearman’s -0.424) and per cent correct (Spearman’s rho 0.565) showed moderate correlations with daily creatine intake. Conclusions: Creatine intake from food is positively associated with selective attention and inhibitory processing in older adults.