Comparison of Cervical Cancer Radiation in Bladder Organs with 10 MV LINAC Energy Radiotherapy Using 3DCRT and IMRT Techniques at Sanglah Hospital Denpasar

Yuli Asri, G. N. Sutapa, I. W. Sudarsana, R. Irhas
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Abstract

A study has been conducted on comparative analysis of cervical cancer radiation to the bladder organ with 10 MV energy LINAC (Linear Accelerator) radiotherapy using the 3DCRT (Three Dimension Conformal Radiotherapy) technique and the IMRT (Intensity Modulated Radiation Therapy) technique at Sanglah Hospital, Denpasar. The 3DCRT and IMRT techniques were compared by analyzing the values ??of the HI (Homogeneity Index), CI (Conformity Index) and radiation dose distribution in the OAR (Organ At Risk), namely the bladder. The data used are 30 cervical cancer patient data with 10 MV photon beam radiotherapy planning and a total radiation dose of 5000 cGy. In calculating the HI and CI values, the data used were radiation dose of 98%, 50%, 2% of target volume and 95% volume on PTV and the average dose on Bladder organs. The data was obtained from the DVH (Dose Volume Histogram) statistics contained in the TPS (Treatment Planning System). The results of the HI value of 0.0818 for the 3DCRT technique and 0.0899 for the IMRT technique with statistical test results obtained the Asimp.Sig (2-tailed) value of 0.056> 0.05 which means it is not significant, while for the results of the CI value of 0.9500 for the 3DCRT technique and 0.9499 for the IMRT technique with statistical test results obtained the Asimp.Sig (2-tailed) value of 0.970> 0.05 which means it is not significant, meanwhile the percentage of the average dose in the bladder organ obtained an average result from the 3DCRT and IMRT irradiation techniques, 96% and 88%, respectively, with statistical test results, the Asimp.Sig (2-tailed) value was 0.000 <0.05, which was significant. Cervical cancer radiation using the IMRT technique is better than the 3DCRT technique because the IMRT technique minimizes the absorbed dose in OAR, it can be seen from the percentage of the average dose in the bladder organ with the IMRT technique getting a smaller dose percentage.
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登巴萨Sanglah医院3DCRT和IMRT技术10毫伏LINAC能量放疗宫颈癌膀胱器官放射的比较
在登巴萨桑格拉医院,采用3DCRT(三维适形放射治疗)技术和IMRT(强度调制放射治疗)方法,对10MV能量LINAC(线性加速器)放射治疗对宫颈癌症膀胱器官的放射进行了比较分析。通过分析3DCRT和IMRT技术的值,对其进行了比较??HI(均匀性指数)、CI(一致性指数)和OAR(危险器官)(即膀胱)中的辐射剂量分布。所用数据为30例癌症宫颈癌患者数据,10 MV光子束放射治疗计划,总辐射剂量为5000 cGy。在计算HI和CI值时,使用的数据是PTV的98%、50%、2%目标体积和95%体积的辐射剂量以及膀胱器官的平均剂量。数据来自TPS(治疗计划系统)中包含的DVH(剂量体积直方图)统计数据。3DCRT技术和IMRT技术的HI值分别为0.0818和0.0899的结果与统计测试结果一起获得了Asimp。Sig(双尾)值0.056>0.05,这意味着它不显著,而对于3DCRT技术的CI值为0.9500和IMRT技术的CI为0.9499的结果,统计测试结果获得了Asimp。Sig(2-尾)值0.970>0.05,这意味着它不显著,同时膀胱器官中平均剂量的百分比获得了3DCRT和IMRT照射技术的平均结果,分别为96%和88%,具有统计学检验结果,Asimp。Sig(2-尾)值为0.000<0.05,具有显著性。使用IMRT技术的宫颈癌症辐射优于3DCRT技术,因为IMRT技术最大限度地减少了OAR中的吸收剂量,从膀胱器官中平均剂量的百分比可以看出,IMRT技术获得的剂量百分比较小。
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