Can Prader-Willi Syndrome Present with Autism ?

Abstract

Affected children usually presented with hypotonia, poor sucking, and failure to thrive during infancy, followed by polyphagia, obesity, and intellectual disability during childhood, and hypogonadism, short stature, and behavioral disturbance during adolescence. In addition, characteristic facial features, such as almond eyes, narrow forehead, thin upper lips, and small hands and feet would be seen2. The prevalence ranges from 1/25,000 to 1/10,000 live born children3.