A Quantification Method to Compare the Value of Surgery and Palliative Care in Patients With Complex Cardiac Disease: A Concept

Gerrah
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Abstract

Patients with complex cardiovascular disease are occasionally considered inoperable due to the high risk of surgical mortality. When the risk of perioperative mortality (POM) is predicted to be too high, surgical intervention is denied, and patients are often referred to palliative care. The risk of POM in cardiac surgery is often calculated using large-scale databases, such as the Society of Thoracic Surgeons (STS) records. The STS risk models, which are regularly updated, are based on large data sets and incorporate precise statistical methods for risk adjustment.1 In general, these calculators provide a percentage value that defines the magnitude of the risk of death, and then an arbitrary range is selected to categorize the procedure as low, medium, or high risk or inoperable status. The STS database does not set a cutoff point or range to define “operability.” Assigning inoperable status to a certain risk rate is problematic, with many ethical, legal, and moral implications, and for this reason, it has mostly remained undefined. In contrast, the lowand medium-risk ranges are easier to define. Another limitation encountered in the STS database is the lack of risk data for less common but very high-risk procedures, such as a triple valve replacement. A common example where risk classification has been defined is in patients who are candidates for surgical vs transcatheter aortic valve replacement. Some groups have described a risk of <4% as low risk,
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比较复杂心脏病患者手术与姑息治疗价值的量化方法:一个概念
由于手术死亡率高,复杂心血管疾病患者有时被认为不适合手术。当围手术期死亡率(POM)的风险被预测过高时,手术干预被拒绝,患者通常被转介到姑息治疗。心脏手术中POM的风险通常使用大型数据库计算,例如胸外科医生协会(STS)的记录。定期更新的STS风险模型是基于大量数据集,并采用精确的统计方法进行风险调整一般来说,这些计算器提供一个百分比值,定义死亡风险的大小,然后选择一个任意范围,将手术分类为低、中、高风险或不可手术状态。STS数据库没有设置一个截止点或范围来定义“可操作性”。将不可手术状态分配给一定的风险率是有问题的,涉及许多伦理、法律和道德方面的问题,因此,它在很大程度上仍未定义。相比之下,低风险和中等风险范围更容易定义。STS数据库遇到的另一个限制是缺乏不常见但高风险手术的风险数据,例如三瓣置换术。确定风险分类的一个常见例子是,选择手术或经导管主动脉瓣置换术的患者。一些团体将风险<4%描述为低风险,
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