Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized molecules

Ö. Yılmaz
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引用次数: 2

Abstract

In this work, new trans-diamide derivatives were synthesized with the reaction between fumaryl chloride and substituted anilines. After successful synthesis of trans-amides, antioxidant activity of all synthesized molecules was investigated via DPPH method and calculated IC50 values. All trans-amides were characterized by 1H-NMR, 13C-NMR, 19F-NMR, GC-MS and FTIR spectroscopic techniques.
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富马酰氯反式二胺衍生物的合成及其清除DPPH活性的测定
本文用富马酰氯与取代苯胺反应合成了新的反式二胺衍生物。成功合成反式酰胺后,通过DPPH法考察所有合成分子的抗氧化活性,并计算IC50值。通过1H-NMR, 13C-NMR, 19F-NMR, GC-MS和FTIR等光谱技术对所有反式酰胺进行了表征。
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来源期刊
CiteScore
1.60
自引率
0.00%
发文量
81
审稿时长
5 weeks
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