Effect of Pharmacist Intervention on Emergency Department Geriatric Patients with Polypharmacy

Rachael Sheehan, Ashley Stajkowski, Lee Hraby, Melanie Mommaerts, Tyler Nichols, Marisa Nichols, A.J. Beuning, Victor Warne
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Abstract

Introduction Polypharmacy is common within the geriatric population due to the commonality of multiple comorbidities and use of multiple providers. The emergency department (ED) is a prime location to capture these patients, especially when they present with chief complaints which may be medication related. Much of this population is prescribed potentially inappropriate medications which increases their risk for adverse drug reactions. Pharmacist review of patient home medication lists has been shown to decrease the number of potentially inappropriate medications, as well as medication-related problems, such as therapeutic duplications and drug interactions. These reductions can increase patient safety. The goal of this project was to evaluate the impact of a comprehensive home medication list review performed by a pharmacist for patients 65 years or older within the ED, in conjunction with ED provider education on potential interventions. Methods This retrospective study compared the average number of home medication modifications made per patient by ED providers at baseline compared to intervention implementation of provider education and pharmacist home medication list review. Additionally, the rate of return to the ED was also compared. Data were collected through manual chart review. Secondary outcomes include total number of pharmacist recommendations, average number of pharmacist recommendations per patient, total number of Medication Management Services (MMS) referrals, total number of MMS consults completed, and total number of MMS interventions. Results There was a statically significant increase in the average number of medications changes per patient on discharge between the two groups with an average of 0.1 changes (SD 0.3, 0.0-2.0) in the pre-intervention group and 0.7 changes (SD 1.5, 0.0-7.0; p<0.001) in the post-intervention group. There also was a statistically significant increase in the percentage of patients with a home medication
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药剂师干预对急诊科老年综合用药患者的影响
引言由于多种合并症的共同性和多个提供者的使用,多药治疗在老年人群中很常见。急诊科(ED)是捕捉这些患者的最佳场所,尤其是当他们提出可能与药物有关的主要投诉时。这一人群中的大部分人被开了可能不合适的药物,这增加了他们出现不良药物反应的风险。药剂师对患者家庭药物清单的审查已被证明可以减少潜在的不合适药物的数量,以及与药物相关的问题,如治疗重复和药物相互作用。这些减少可以提高患者的安全性。该项目的目标是评估药剂师对急诊科65岁或65岁以上患者进行的全面家庭药物清单审查的影响,同时评估急诊科提供者对潜在干预措施的教育。方法本回顾性研究比较了ED提供者在基线时对每位患者进行的家庭药物修改的平均次数,以及提供者教育和药剂师家庭药物清单审查的干预实施情况。此外,还比较了ED的回报率。数据是通过手动图表审查收集的。次要结果包括药剂师推荐总数、每位患者药剂师推荐的平均数、药物管理服务(MMS)转诊的总数、完成的MMS咨询的总数以及MMS干预的总数。结果两组患者出院时的平均药物变化次数静态显著增加,干预前组平均变化0.1次(SD 0.3,0.0-2.0),干预后组平均变化0.7次(SD 1.5,0.0-7.0;p<0.001)。在家服药的患者比例也有统计学上的显著增加
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