Antibiotic Resistance Profile in Co-Infecting Bacteria Isolated from Sheep Dipslaying Orf Lesions

Abstract

Antibiotic resistance in veterinary medicine poses lately increasing risks in therapeutic success and threatens the life of patients with various bacterial infections. Environmental bacteria are very likely to develop on the initial lesions induced by orf virus in sheep, worsening the development and prognosis of the disease. The research aimed at verifying the hypothesis that the persistence of the bacteria and thus, increased severity of the orf lesions is residing in the high antibiotic resistance of the co-infecting bacteria. The antibiotics used were gentamicine, cefuroxime, amoxicilline clavulanic acid, enrofloxacin, ciprofloxacin, penicillin and thrimetoprim. Multi antibiotic resistance indices were calculated for each strain. Based on the MAR index, at least two of the investigated environmental bacteria strains could further complicate orf lesions and delay the positive effects of the antibiotic therapy.