A case of sellar epidermoid tumour with haemorrhage

A. Kumar A., Geetha Gopal K.
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Abstract

Introduction: Intracranial epidermoid cysts are congenital inclusion tumours. Cerebellopontine angle and parasellar locations are the common locations. This is a report of an intrasellar epidermoid cyst with haemorrhage, which is rare. Case report: A 70-year-old female presented with bifrontal headache, vertigo, and nasal discharge. Contrast-enhanced Magnetic resonance imaging[MRI] showed heterogeneously enhancing lesion in sella turcica. Internal hemorrhagic foci were seen. Computed tomography[CT] scan showed a slightly hyperdense tumour of sella. Transnasal transsphenoidal excision was done. Hemorrhagic and colloid material came out. Histopathological examination showed cyst lined by stratified squamous epithelium with keratohyalin granules and keratin flakes, suggestive of an epidermoid cyst. Discussion: Usually epidermoid cyst is hypodense in CT scan. But hyperdensity can occur due to calcification of keratinized debris, increased protein content, and recurrent haemorrhage. Enhancement with gadolinium in MRI is mild and in cyst wall. Haemorrhage and enhancement are probably due to foreign body granulation tissue developing from leakage.
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鞍区表皮样肿瘤伴出血1例
颅内表皮样囊肿是一种先天性包涵性肿瘤。桥小脑角和鞍旁是常见的位置。这是一例罕见的鞍内表皮样囊肿并发出血。病例报告:一名70岁女性,表现为双额头痛、眩晕和流鼻液。磁共振造影显示蝶鞍病变不均匀强化。可见内出血灶。计算机断层扫描显示鞍区轻度高密度肿瘤。经鼻蝶窦切除。出血性和胶体物质出来了。组织病理学检查显示囊肿内衬层状鳞状上皮,有角透明素颗粒和角蛋白薄片,提示表皮样囊肿。讨论:通常表皮样囊肿在CT扫描表现为低密度。但由于角化碎片的钙化、蛋白质含量增加和复发性出血,可发生高密度。MRI钆增强轻度,且位于囊壁。出血和强化可能是由渗漏形成的异物肉芽组织引起的。
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