ЛЕКТИНОХІМІЧНА ХАРАКТЕРИСТИКА ЗАЛОЗИСТОЇ ЗОНИ СЛИЗОВОЇ ОБОЛОНКИ ТВЕРДОГО ПІДНЕБІННЯ ЩУРІВ ПІСЛЯ ДІЇ 1 % ЕФІРУ МЕТАКРИЛОВОЇ КИСЛОТИ

Problemi ekologiyi ta meditsini Pub Date : 2022-04-15 DOI:10.31718/mep.2022.26.1-2.03

Галина Анатоліївна Єрошенко, Юлія Володимирівна Тимошенко, Костянтин Васильович Шевченко, Ольга Дмитриевна Лисаченко, Н. А. Улановська-циба

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Abstract

Decreased secretory activity of the salivary glands leads to deterioration of the general condition and aggravation of dental diseases in patients, which determines the relevance of the chosen topic. We identified changes in the morpho-functional state of the mucous membrane of the hard palate under the conditions of experimental hyposalivation by the method of lectin probing. This method is significantly superior to traditional methods of histochemical verification of carbohydrates due to its sensitivity and selectivity for the detection of these molecular structures. HPA lectin was used to identify the expression of carbohydrate determinants in the structural elements of the glandular zone of the mucous membrane of the hard palate in rats.

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唾液腺分泌活性的降低导致患者一般情况的恶化和牙齿疾病的加重，这决定了所选主题的相关性。我们用凝集素探针的方法鉴定了实验条件下硬腭粘膜形态功能状态的变化。由于该方法对这些分子结构的检测具有灵敏度和选择性，因此明显优于传统的碳水化合物组织化学验证方法。采用HPA凝集素检测大鼠硬腭粘膜腺区结构元件中碳水化合物决定因子的表达。

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Problemi ekologiyi ta meditsini

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4 weeks