Differential Profile of High-Performance Adults with Attention Deficit Hyperactivity Disorder

Pablo L. López, T. Testa
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Abstract

Objective: To compare the neurocognitive profile of a subgroup of patients with ADHD who have a high academic-occupational functioning vs. patients with low functioning. Method: A total of 50 adults with ADHD, 10 with high academic-occupational functioning (ADHD/HF), 20 with low academic-occupational functioning (ADHD-LF), and 20 healthy controls were assessed with a standard neuropsychological battery. Independent sample tests and logistic regression were calculated to compare the performance of the three groups and to identify predictor variables. Results: Statistically significant differences were found in the forward digits subtest between the subtypes of ADHD, but not between ADHD-HF and controls, nor between controls and ADHD-LF. In matrix reasoning subtest, significantly lower performances were registered between both ADHD groups compared to the control group. In the letter number subtest, ADHD-LF obtained a significant lower performance than the control group, but the ADHD-HF group do not differ with the other two groups. Finally, regarding to the binary logistic regression analysis, it could be observed that the only variable that best predicted belonging to these groups has been forward digits, which according to the data of the model would be a protection factor. Conclusion: The profile of patients with high socio-occupational performance was characterized by a better conservation of working memory and the capacity for sustained attention, and a lower tendency to distraction.
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高绩效成人注意缺陷多动障碍的差异特征
目的:比较具有高学术-职业功能的ADHD患者亚组与具有低功能的患者的神经认知特征。方法:采用标准神经心理测验对50名患有多动症的成年人、10名具有高学术职业功能(ADHD/HF)的成年人、20名具有低学术职业功能的成年人和20名健康对照进行评估。计算独立样本检验和逻辑回归,以比较三组的表现并确定预测变量。结果:ADHD各亚型的前指子测验存在统计学上的显著差异,但ADHD-HF与对照组之间以及对照组与ADHD-LF之间没有统计学上的差异。在矩阵推理子测验中,与对照组相比,两组ADHD的表现都明显较低。在字母数字子测试中,ADHD-LF的表现明显低于对照组,但ADHD-HF组与其他两组没有差异。最后,关于二元逻辑回归分析,可以观察到,唯一最能预测属于这些组的变量是前向数字,根据模型的数据,这将是一个保护因素。结论:高社会职业表现患者的特点是工作记忆和持续注意能力得到更好的保护,注意力分散的倾向较低。
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