Evolution of Clinical Care in COVID-Infected Solid Organ Transplant Recipients.

IF 2.4 Q2 SURGERY Current Transplantation Reports Pub Date : 2022-01-01 Epub Date: 2022-05-31 DOI:10.1007/s40472-022-00368-z
Rachel Sigler, Victor Chen, Nancy Law
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Abstract

Purpose of review: In this review, we aim to summarize the evolution of care for the solid organ transplant recipient (SOTR) with COVID-19 disease, based on the current published guidelines and our center's experience.

Recent findings: Oral antiviral medications and monoclonal antibodies are now used with the goal to prevent severe disease. Immunomodulating drugs in addition to antivirals have been used in the treatment of severe COVID-19.

Summary: With the ongoing pandemic and unique challenges posed by the SOTR, understanding the risk and advancing management and treatment of COVID-19 infections are imperative to the successful care of a transplant recipient. There are many ongoing clinical trials being conducted in hopes of developing novel therapeutics towards COVID-19.

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新型冠状病毒感染实体器官移植受者临床护理的演变
综述的目的:在这篇综述中,我们旨在根据目前公布的指南和本中心的经验,总结对患有 COVID-19 疾病的实体器官移植受者(SOTR)的护理发展:最新发现:目前口服抗病毒药物和单克隆抗体的使用旨在预防严重疾病。除了抗病毒药物外,免疫调节药物也被用于治疗严重的 COVID-19。总结:随着大流行病的不断发展和 SOTR 带来的独特挑战,了解 COVID-19 感染的风险并推进其管理和治疗对于移植受者的成功治疗至关重要。目前正在进行多项临床试验,希望开发出针对 COVID-19 的新型疗法。
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来源期刊
CiteScore
3.40
自引率
4.80%
发文量
34
期刊介绍: Under the guidance of Dr. Dorry Segev, from Johns Hopkins, Current Transplantation Reports will provide an in-depth review of topics covering kidney, liver, and pancreatic transplantation in addition to immunology and composite allografts.We accomplish this aim by inviting international authorities to contribute review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists.  By providing clear, insightful balanced contributions, the journal intends to serve those involved in the field of transplantation.
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