Evaluation of Nutritive, Non-Nutritive Contents and Antioxidant Activity of Polyherbal Formulations

Q3 Pharmacology, Toxicology and Pharmaceutics Current Trends in Biotechnology and Pharmacy Pub Date : 2021-05-31 DOI:10.5530/CTBP.2021.2.14
H. Patnala, G. Ramana, B. Babu
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引用次数: 1

Abstract

Efficacy and safety of polyherbal formulations was based on non-nutritive and nutritive contents. Present work deals with estimation of non-nutritive phytochemicals such as total phenolic and flavonoid compounds, antioxidant activity and nutritive elements and heavy metals content of polyherbal formulations of Sitopaladi and Talisadichurna. Results have revealed that total phenolic and flavonoid concentrations of Sitopaladichurna extracts were rich in SC1 followed by SC3, SC2 and SC4, and in case of Talisadichurna extracts, the order was TC3 followed by TC2, TC1 and TC4. This specifies that substantial positive linear correlation occurred between total phenolic and flavonoid contents. The herbal formulations disclosed higher scavenging ability with DPPH, ABTS.+ and reducing power than standard ascorbic acid. The extracts displayed better antioxidant activity which also contains higher phenolic contents, indicating that there was a correlation. Findings unveil that herbal formulations were found to be rich source of macro and micronutrients. Furthermore, heavy metals such as Arsenic, Chromium, Cadmium and Lead were not detected at noticeable concentrations in herbal medicines and Mercury concentrations were below the detection limit (< 0.3 mg/kg).
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中草药制剂营养成分、非营养成分及抗氧化活性的评价
多羟基制剂的有效性和安全性基于非营养和营养成分。目前的工作涉及对西托帕拉迪和Talisadichurna的多羟基制剂的非营养性植物化学物质,如总酚类和类黄酮类化合物、抗氧化活性以及营养元素和重金属含量的估计。结果表明,西托帕拉迪丘纳提取物的总酚类和类黄酮浓度富含SC1,其次是SC3、SC2和SC4,而在Talisadichurna提取物的情况下,顺序为TC3,其次是TC2、TC1和TC4。这表明总酚类和类黄酮含量之间存在显著的正线性相关性。草药制剂显示DPPH、ABTS.+具有更高的清除能力并且比标准抗坏血酸降低功率。提取物显示出更好的抗氧化活性,其中还含有更高的酚类含量,表明存在相关性。研究结果表明,草药配方富含宏量和微量营养素。此外,草药中未检测到明显浓度的砷、铬、镉和铅等重金属,汞浓度低于检测限(<0.3 mg/kg)。
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来源期刊
Current Trends in Biotechnology and Pharmacy
Current Trends in Biotechnology and Pharmacy Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
0.70
自引率
0.00%
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0
期刊介绍: The Association of Biotechnology and Pharmacy (ABAP) will be useful to form a forum for scientists so that they can bring together to discuss and find scientific solutions to the problems of society. The annual meetings will help the members to share their knowledge and publish their research knowledge particularly by members and fellows of the Association and special care will be taken to provide an opportunity for young scientists. Besides this the association is planned to organize symposia, seminars and workshops on current developments of Biotechnology and Pharmacy particularly on the subject of current scientific interest, and the proceedings of which will be published regularly. And in view of the vast development of science and to disseminate the problems in publication of research work, an international journal of Current Trends in Biotechnology and Pharmacy has been started by ABAP.
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