{"title":"Evaluation of Nutritive, Non-Nutritive Contents and Antioxidant Activity of Polyherbal Formulations","authors":"H. Patnala, G. Ramana, B. Babu","doi":"10.5530/CTBP.2021.2.14","DOIUrl":null,"url":null,"abstract":"Efficacy and safety of polyherbal formulations was based on non-nutritive and nutritive contents. Present work deals with estimation of non-nutritive phytochemicals such as total phenolic and flavonoid compounds, antioxidant activity and nutritive elements and heavy metals content of polyherbal formulations of Sitopaladi and Talisadichurna. Results have revealed that total phenolic and flavonoid concentrations of Sitopaladichurna extracts were rich in SC1 followed by SC3, SC2 and SC4, and in case of Talisadichurna extracts, the order was TC3 followed by TC2, TC1 and TC4. This specifies that substantial positive linear correlation occurred between total phenolic and flavonoid contents. The herbal formulations disclosed higher scavenging ability with DPPH, ABTS.+ and reducing power than standard ascorbic acid. The extracts displayed better antioxidant activity which also contains higher phenolic contents, indicating that there was a correlation. Findings unveil that herbal formulations were found to be rich source of macro and micronutrients. Furthermore, heavy metals such as Arsenic, Chromium, Cadmium and Lead were not detected at noticeable concentrations in herbal medicines and Mercury concentrations were below the detection limit (< 0.3 mg/kg).","PeriodicalId":10980,"journal":{"name":"Current Trends in Biotechnology and Pharmacy","volume":"15 1","pages":"124-132"},"PeriodicalIF":0.0000,"publicationDate":"2021-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Trends in Biotechnology and Pharmacy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5530/CTBP.2021.2.14","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
引用次数: 1
Abstract
Efficacy and safety of polyherbal formulations was based on non-nutritive and nutritive contents. Present work deals with estimation of non-nutritive phytochemicals such as total phenolic and flavonoid compounds, antioxidant activity and nutritive elements and heavy metals content of polyherbal formulations of Sitopaladi and Talisadichurna. Results have revealed that total phenolic and flavonoid concentrations of Sitopaladichurna extracts were rich in SC1 followed by SC3, SC2 and SC4, and in case of Talisadichurna extracts, the order was TC3 followed by TC2, TC1 and TC4. This specifies that substantial positive linear correlation occurred between total phenolic and flavonoid contents. The herbal formulations disclosed higher scavenging ability with DPPH, ABTS.+ and reducing power than standard ascorbic acid. The extracts displayed better antioxidant activity which also contains higher phenolic contents, indicating that there was a correlation. Findings unveil that herbal formulations were found to be rich source of macro and micronutrients. Furthermore, heavy metals such as Arsenic, Chromium, Cadmium and Lead were not detected at noticeable concentrations in herbal medicines and Mercury concentrations were below the detection limit (< 0.3 mg/kg).
期刊介绍:
The Association of Biotechnology and Pharmacy (ABAP) will be useful to form a forum for scientists so that they can bring together to discuss and find scientific solutions to the problems of society. The annual meetings will help the members to share their knowledge and publish their research knowledge particularly by members and fellows of the Association and special care will be taken to provide an opportunity for young scientists. Besides this the association is planned to organize symposia, seminars and workshops on current developments of Biotechnology and Pharmacy particularly on the subject of current scientific interest, and the proceedings of which will be published regularly. And in view of the vast development of science and to disseminate the problems in publication of research work, an international journal of Current Trends in Biotechnology and Pharmacy has been started by ABAP.