{"title":"Progress of brain functional MRI in inflammatory bowel disease","authors":"Lu Li","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.01.018","DOIUrl":null,"url":null,"abstract":"炎症性肠病（IBD）包括克罗恩病和溃疡性结肠炎。脑-肠轴可通过心理-神经-内分泌-免疫调节在IBD发生、发展中发挥重要作用，通过MRI来观察及研究IBD患者的脑结构及脑功能异常，特别是脑功能异常的观察，有利于更深层次地理解IBD的发病机制，并从神经方向寻找新的治疗方法可能有效减轻肠道炎症或缓解腹痛症状。","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zhonghua fang she xue za zhi Chinese journal of radiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.01.018","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Inflammatory bowel disease (IBD) includes Crohn's disease and ulcerative colitis. The brain gut axis can play an important role in the occurrence and development of IBD through psychological, neural, endocrine, and immune regulation. Observing and studying the brain structure and functional abnormalities of IBD patients through MRI, especially the observation of brain functional abnormalities, is conducive to a deeper understanding of the pathogenesis of IBD and finding new treatment methods from the neural perspective that may effectively alleviate intestinal inflammation or alleviate abdominal pain symptoms.
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