Vitamin D Levels are found to be higher in Gestational Diabetics in Vitamin D Depleted Population

Abstract

Objective: Vitamin D levels are studied in Gestational Diabetes in many researches. Our aim is to investigate the relationship of vitamin D deficiency with gestational diabetes mellitus (GDM) in pregnancy. Methods: In this study, 210 Pregnant women were included, of them 108 had GDM, 102 were controls. 25-hydroxyvitamin D (25(OH)D) levels of GDM group were compared with healthy pregnant controls. The maternal and fetal outcomes were recorded. Results: GDM group had significantly higher mean 25(OH)D (11.8±8.0 ng/ml) compared to controls (7.7±6.1 ng/ml, p<0.01). There was no correlation of vitamin D levels with; maternal age, Apgar levels, birth week and fetal weight. Furthermore, there was no correlation of 25(OH)D levels with mode of delivery, intensive care need of new-born and macrosomia. Conclusions: Although there are numerous reports about positive correlation between vitamin D deficiency and GDM in pregnancy, we found the opposite. In severe vitamin D deficiency, the mechanisms may differ and should be identified further.