Population Attributable Risk of Cardiovascular Disease Associated with not Meeting Physical Activity Guidelines in Montana Adults

Peter D. Hart
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Abstract

Background : Coronary heart disease (CHD) is the number 1 cause of death in United States (U.S.) with stroke also a leading killer at number 5. Aside from decreased quality of life and increased years of potential life lost (YPLL), cardiovascular disease (CVD) has a major impact on health care costs. While many CVD events can be prevented by adopting a healthy lifestyle, data quantifying this are sparse. The aim of this study was to assess the proportion of CVD cases that can be attributed to not meeting physical activity (PA) guidelines in a specific adult population. Methods : The Montana Behavioral Risk Factor Surveillance System (BRFSS, 2019) was used for this study. A dichotomous PA variable was created indicating whether or not a participant met current PA guidelines. Seven other healthy lifestyle variables were created and included smoking, alcohol consumption, overweight status, vegetable consumption, fruit consumption, and, health coverage. Three different outcome variables were used and included CHD, stroke, and CVD (CHD or stroke). Logistic regression was used to examine the relationship between PA and each CVD outcome while controlling for healthy lifestyle factors and sociodemographic variables. Population attributable risk (PAR) percentages were computed substituting PA odds ratio (OR) values into Levin's formula. Results : Prevalence of reported CHD, stroke, and CVD were 6.7%, 3.1%, and 8.7%, respectively. Additionally, prevalence of each CVD outcome was significantly ( p s < .05) higher in adult groups not meeting PA guidelines, as compared to their more active counterparts. PA was significantly related to CHD (OR = 1.36, 95% CI: 1.04 – 1.79) and CVD (OR = 1.32, 95% CI: 1.02 – 1.71) in fully adjusted models and suggestively related to stroke (OR = 1.24, 95% CI: 0.81 – 1.91). PAR analyses indicated that approximately 12.1%, 8.4%, and 10.8% of CHD, stroke, and CVD cases (respectively) could be prevented in Montana with PA intervention. Conclusion : This study found that after controlling for several healthy lifestyle factors, not meeting PA guidelines independently contributes to a sizable number of CVD cases in Montana. Health promotion programming leaders should use such PAR statistics to drive the needs assessment process and plan for PA interventions.
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蒙大拿州成年人不符合身体活动指南相关的心血管疾病人群归因风险
背景:在美国,冠心病(CHD)是第一大死亡原因,中风也是第五大杀手。除了生活质量下降和潜在寿命损失(YPLL)增加外,心血管疾病(CVD)对医疗保健成本也有重大影响。虽然许多CVD事件可以通过采取健康的生活方式来预防,但量化这一点的数据很少。本研究的目的是评估特定成年人群中可归因于不符合体育活动(PA)指南的CVD病例比例。方法:本研究采用蒙大拿州行为危险因素监测系统(BRFSS,2019)。创建了一个二分法PA变量,指示参与者是否符合当前PA指南。创建了其他七个健康生活方式变量,包括吸烟、饮酒、超重状态、蔬菜消费、水果消费和健康覆盖率。使用了三个不同的结果变量,包括CHD、中风和CVD(CHD或中风)。在控制健康生活方式因素和社会人口统计学变量的同时,使用Logistic回归来检验PA和每种CVD结果之间的关系。计算人群归因风险(标准杆数)百分比,将PA比值比(OR)值代入Levin公式。结果:报告的CHD、中风和CVD的患病率分别为6.7%、3.1%和8.7%。此外,与更活跃的对照组相比,不符合PA指南的成年组的每种CVD结果的患病率显著较高(p s<.05)。在完全调整的模型中,PA与CHD(OR=1.36,95%CI:1.04–1.79)和CVD(OR=1.32,95%CI:0.02–1.71)显著相关,并暗示与中风相关(OR=1.24,95%CI:8.81–1.91)。标准杆数分析表明,在蒙大拿州,通过PA干预,可以预防约12.1%、8.4%和10.8%的CHD、中风和CVD病例。结论:本研究发现,在控制了几种健康的生活方式因素后,不符合PA指南会导致蒙大拿州相当多的CVD病例。健康促进方案编制领导人应利用标准杆数统计数据推动需求评估过程和PA干预计划。
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