Rational Dispensing of Oral Dosage Forms of Medicines to Children and Its Associated Factors in South West Ethiopia

IF 1.7 Q2 PEDIATRICS Pediatric health, medicine and therapeutics Pub Date : 2022-04-01 DOI:10.2147/PHMT.S360383
Fikadu Ejeta, Diriba Feyisa, Temesgen Aferu, Jafer Siraj, Demeke Melkam, Ahmed Ali
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Abstract

Introduction Obstacles encountered when maintaining excellent dispensing practices for children include a lack of age-appropriate dosage forms, a shortage of medications in appropriate strengths for children, a lack of appetizing drugs, and a lack of competence in pediatric pharmacy. These difficulties contribute to ineffective dispensing procedures and an urgent need to study whether oral dose forms of medications are dispensed to children in a rational way. Objective The purpose of this study is to evaluate the rational dispensing of oral dosage forms of medicines to children, as well as the factors that influence this practice. Methods Using validated indicators, a cross-sectional study design was utilized to analyze the rational dispensing practice of oral dosage forms of medicines administered to children under the age of 12 years in seven pharmacies and two drug stores over a one-month period. Results and discussions Out of 810 medicines, 11.7% and 4% were irrationally manipulated, 5.8% and 1.8% needed manipulation, 3.7% and 0.2% were alternatively dispensed, 8.8% and 7.5% of the medicines had correct advice on their label and also 745 medicines were adequately labeled in the hospital and the selected drug stores. In this study, 92% of medicines were adequately labeled and had sufficient advice on their labels, 15.3% of medicines were irrationally manipulated and around 7.7% of the dosage forms needed manipulation during dispensing. The type of medicine retail outlet had a significant effect on the percentage of instances where alternative solid oral dosage forms were dispensed (p = 0.003), the percentage of dosage forms were adequately labeled (p = 0.008), and the percentage of dosage forms were irrationally manipulated before dispensing (p = 0.001). Conclusion The rational dispensing practice of oral dosage forms of medicines was relatively poor and there is room for improvement.
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埃塞俄比亚西南部儿童口服剂型的合理分配及其相关因素
引言在为儿童保持良好的配药实践时遇到的障碍包括缺乏适合年龄的剂型、缺乏适合儿童服用的适当强度的药物、缺乏开胃药以及缺乏儿科药学能力。这些困难导致配药程序无效,迫切需要研究是否以合理的方式向儿童配药。目的本研究旨在评估儿童口服剂型的合理分配,以及影响这种做法的因素。方法采用经验证的指标,采用横断面研究设计,分析7家药店和2家药店一个月内12岁以下儿童口服剂型药物的合理配药实践。结果和讨论在810种药物中,11.7%和4%被非理性操纵,5.8%和1.8%需要操纵,3.7%和0.2%被交替分配,8.8%和7.5%的药物标签上有正确的建议,745种药物在医院和选定的药店有充分的标签。在这项研究中,92%的药物都有充分的标签,标签上有足够的建议,15.3%的药物被非理性地操纵,大约7.7%的剂型在配药过程中需要操纵。药品零售店的类型对分配替代固体口服剂型的情况百分比有显著影响(p=0.003)、剂型被充分标记的百分比(p=0.008),结论口服剂型的合理配药实践相对较差,还有改进的空间。
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