The health effects of 14 weeks of physical activity in a real-life setting for adults with intellectual disabilities

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2022-05-19 DOI:10.1101/2022.05.17.22272069

Laurits Munk Højberg, E. W. Helge, J. Pingel, J. Wienecke

{"title":"The health effects of 14 weeks of physical activity in a real-life setting for adults with intellectual disabilities","authors":"Laurits Munk Højberg, E. W. Helge, J. Pingel, J. Wienecke","doi":"10.1101/2022.05.17.22272069","DOIUrl":null,"url":null,"abstract":"Background: Individuals with intellectual disabilities (ID) have a reduced physical health compared to the general population, and one of the main contributors is inactivity. Aim: To investigate how 14 weeks of physical activity (PA) in a real-life setting affects cardiovascular fitness, body composition and bone health of adults with ID. Methods: Adults with ID were recruited into a PA-group or a control group (CON). The PA-group participated in 14 weeks of PA. Body composition, cardiovascular fitness and bone health were assessed before and after the intervention. Outcomes & results: Cardiovascular fitness and body composition improved from pre to post within the PA-group: Heart rates (HR) during the last 30 seconds of two increments of a treadmill test, were reduced (3.2 km/h: -4.4 bpm, p<0.05; 4.8 km/h: -7.5 bpm, p<0.001) and fat mass was reduced (-1.02 kg, p<0.05). Between-group differences in favour of the PA-group, were observed in whole body bone mineral density (BMD) (0.024 g/cm2, p<0.05) and in BMD of the left femur neck (0.043 g/cm2, p<0.05). Conclusions & Implications: Fourteen weeks of PA increase cardiovascular fitness, reduced fat mass and improved BMD in the weight-bearing skeleton in the PA-group. Increased and regular PA seems to be a promising tool to promote physical health in adults with ID.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2022-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2022.05.17.22272069","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Individuals with intellectual disabilities (ID) have a reduced physical health compared to the general population, and one of the main contributors is inactivity. Aim: To investigate how 14 weeks of physical activity (PA) in a real-life setting affects cardiovascular fitness, body composition and bone health of adults with ID. Methods: Adults with ID were recruited into a PA-group or a control group (CON). The PA-group participated in 14 weeks of PA. Body composition, cardiovascular fitness and bone health were assessed before and after the intervention. Outcomes & results: Cardiovascular fitness and body composition improved from pre to post within the PA-group: Heart rates (HR) during the last 30 seconds of two increments of a treadmill test, were reduced (3.2 km/h: -4.4 bpm, p<0.05; 4.8 km/h: -7.5 bpm, p<0.001) and fat mass was reduced (-1.02 kg, p<0.05). Between-group differences in favour of the PA-group, were observed in whole body bone mineral density (BMD) (0.024 g/cm2, p<0.05) and in BMD of the left femur neck (0.043 g/cm2, p<0.05). Conclusions & Implications: Fourteen weeks of PA increase cardiovascular fitness, reduced fat mass and improved BMD in the weight-bearing skeleton in the PA-group. Increased and regular PA seems to be a promising tool to promote physical health in adults with ID.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

在现实生活中对智障成年人进行14周体育活动对健康的影响

背景:与一般人群相比，智力残疾者(ID)的身体健康状况较差，其中一个主要原因是缺乏活动。目的:研究现实生活中14周的身体活动(PA)如何影响ID成人的心血管健康、身体成分和骨骼健康。方法:将成年ID患者分为pa组和对照组(CON)。PA组参加14周的PA治疗。在干预前后评估身体成分、心血管健康和骨骼健康。结果和结果:在pa组中，心血管健康和身体成分从术前到术后有所改善:跑步机试验两次增加的最后30秒心率(HR)降低(3.2 km/h: -4.4 bpm, p<0.05;4.8 km/h: -7.5 bpm, p<0.001)，脂肪量减少(-1.02 kg, p<0.05)。pa组小鼠全身骨密度(BMD)为0.024 g/cm2, p<0.05;左股骨颈骨密度为0.043 g/cm2, p<0.05。结论和意义:14周的PA增加了心血管健康，减少了脂肪量，改善了负重骨骼的骨密度。增加和有规律的PA似乎是促进ID成人身体健康的有希望的工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.