(E)-N’-(1-(Benzofuran-2-yl)ethylidene)-1-(4-Methoxyphenyl)-5-Methyl-1H-1,2,3-Triazole-4-Carbohydrazide

IF 0.6 Q4 CHEMISTRY, ORGANIC Molbank Pub Date : 2023-06-03 DOI:10.3390/m1657
Bakr F. Abdel-Wahab, M. Bekheit, Benson M. Kariuki, Gamal A. El-Hiti
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Abstract

The reaction of equimolar equivalents of 1-(4-methoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carbohydrazide (1) and 2-acetylbenzofuran (2) in anhydrous ethanol containing a catalytic amount of concentrated hydrochloric acid under reflux for 2 h gave (E)-N’-(1-(benzofuran-2-yl)ethylidene)-1-(4-methoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carbohydrazide (3) in 86% yield. The structure of the title heterocycle 3 was confirmed using nuclear magnetic resonance and X-ray diffraction.
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(E) -N'-(1-(苯并呋喃-2-基)亚乙基)-1-(4-甲氧基苯基)-5-甲基-1H-1,2,3-三唑-4-碳酰肼
等摩尔当量的1-(4-甲氧基苯基)-5-甲基-1H-1,2,3-三唑-4-甲酰肼(1)和2-乙酰基苯并呋喃(2)在含有催化量的浓盐酸的无水乙醇中回流反应2小时,得到(E)-N’-(1-(苯并呋喃-2-基)亚乙基)-1-(4-甲基苯基)-5甲基-1H-11,2,3-三噻唑-4-甲酰亚胺(3),产率86%。使用核磁共振和X射线衍射证实了标题杂环3的结构。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Molbank
Molbank Chemistry-Physical and Theoretical Chemistry
CiteScore
0.70
自引率
33.30%
发文量
174
审稿时长
11 weeks
期刊介绍: •organic synthesis •biosynthesis •extraction and purification •natural product derivatives •structural elucidation (X-ray crystallography, NMR, etc.)
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