Rhinoscleroma: report of 2 cases and literature review

M. Ndiaye, M. Diouf, C. Ndiaye, Abdou Sy, Malick, Ndiaye, A. Tall, E. Diom, I. Ndiaye, R. Diouf
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引用次数: 1

Abstract

Background: Rhinoscleroma is a chronic and specific granulomatous infectious disease caused by enterobacteria of the family Klebsiella: "Klebsiella rhinoscleromatis"; it reaches the nasal cavities in 95% of cases. The objective of our study is to report the clinical, diagnostic and therapeutic aspects of our patients. Observations/Medical findings: The study took place at the ENT department of the Fann National University Hospital Center in Dakar, and it was based on two female subjects who are 26 and 60 years old, respectively. The medical examination of the subjects indicated a granulomatous lesion blocking the two nasal cavities. A biopsy performed on each patient revealed a rhinoscleroma. Both patients received doxycycline-based medical treatment with endoscopic endonasal surgery like "Debulking." The patients all recovered nasal breathing after airway clearance. However, we noted a scar retraction of the nasal cavities in the first patient. Conclusions: As the disease recurs, rhinoscleroma is becoming more and more a cosmopolitan affection. The diagnosis is histological. Well-conducted medical treatment allows healing in early forms while surgery is complementary in advanced forms. The fear of a recurrence calls for an extended follow-up.
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鼻动脉粥样硬化2例报告及文献复习
背景:鼻硬化瘤是由克雷伯氏菌属肠杆菌引起的一种慢性特异性肉芽肿性感染性疾病。95%的病例会到达鼻腔。我们研究的目的是报告患者的临床、诊断和治疗方面的情况。观察/医学发现:该研究在达喀尔范恩国立大学医院中心的耳鼻喉科进行,以两名分别为26岁和60岁的女性为研究对象。医学检查显示两个鼻腔有肉芽肿阻塞。每个病人的活组织检查显示一个鼻硬化瘤。两名患者都接受了以强力霉素为基础的药物治疗,并进行了内窥镜鼻内手术,如“减体积”。所有患者经气道通畅后均恢复鼻腔呼吸。然而,我们注意到第一个患者的鼻腔有瘢痕缩回。结论:随着疾病的复发,鼻硬化瘤越来越成为一种世界性疾病。病理诊断。良好的医学治疗可以使早期的疾病痊愈,而手术是晚期疾病的补充。由于担心复发,需要延长随访时间。
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