{"title":"Langerhans Cell Histiocytosis on Fine Needle Aspiration Cytology","authors":"S. Shaikh, Eman Al Jufairi, Rabab Al Khayyat","doi":"10.12816/0047637","DOIUrl":null,"url":null,"abstract":"175 LCH is a rare disease affecting predominantly children and young adults. LCH is considered a neoplasm of the mononuclear phagocytic immunoregulatory system. It is characterized by clonal proliferation of Langerhans cells (LCs). LCH has three categories: eosinophilic granuloma (solitary and most common), Hand-Schuller-Christian disease (multifocal unisystem form) and Letterer-Siwe syndrome (multifocal multisystem form)1,2. The diagnostic cytological features of LCH include high cellularity composed of sheets of characteristic Langerhans cell with large kidney-shaped nuclei admixed with eosinophils, neutrophils, macrophages, and lymphocytes.","PeriodicalId":0,"journal":{"name":"","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.12816/0047637","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
175 LCH is a rare disease affecting predominantly children and young adults. LCH is considered a neoplasm of the mononuclear phagocytic immunoregulatory system. It is characterized by clonal proliferation of Langerhans cells (LCs). LCH has three categories: eosinophilic granuloma (solitary and most common), Hand-Schuller-Christian disease (multifocal unisystem form) and Letterer-Siwe syndrome (multifocal multisystem form)1,2. The diagnostic cytological features of LCH include high cellularity composed of sheets of characteristic Langerhans cell with large kidney-shaped nuclei admixed with eosinophils, neutrophils, macrophages, and lymphocytes.