Abdeljalil Talhaoui, Y. Aboussaleh, Samir Bikri, F. Z. Rouim, A. Ahami
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引用次数: 1
Abstract
The Mediterranean Diet has long been regarded as one of thepromising strategies for the prevention of cognitive impairmentand Alzheimer's disease. Aim: This study aimed to determinethe association between adherence to a MedDiet and the riskof cognitive impairment (CI) among the elderly in Morocco.Due to their complete data, a sample of 172 (56.4% men) from 237 subjects were included in our study. Cognitive functions were assessed by the MMSE test (Mini-Mental State Examina- tion). Adherence to a MedDiet was assessed using a validated questionnaire based on weekly consumption of the seven main MedDiet foods: non-refined cereals, potatoes, fruits (whole or in juice), vegetables (cooked or as salad), legumes, fish, olive oil, and three foods consumed less frequently in a MedDiet: red meats, poultry, and full-fat dairy products. A binary logistic regression was performed, with cognitive function as the dependent variable MedDiet adherence score as well as the aliment consumption frequency associated with CI in the bivariate analysis as an independent variable.The binary logistic regression adjusted for confounding vari- ables revealed that adherence to a MedDiet is not associated with a lower risk of cognitive impairment (ORa= 0.928; 95% CI; [0.831-1.037]) (ORa: Adjusted Odd Ratio; 95% CI: 95% of Confidence Interval). However, only Olive Oil consumption was a protective factor against CI (ORa= 0.882; 95% CI; [0.815-0.953]).
长期以来,地中海饮食一直被认为是预防认知障碍和阿尔茨海默病的有希望的策略之一。目的:本研究旨在确定摩洛哥老年人坚持MedDiet与认知障碍(CI)风险之间的关系。由于他们的完整数据,我们的研究包括237名受试者中的172名(56.4%的男性)样本。认知功能通过MMSE测试(Mini Mental State Examination)进行评估。根据每周食用的七种主要MedDiet食物:非精制谷物、土豆、水果(整份或果汁)、蔬菜(煮熟或作为沙拉)、豆类、鱼类、橄榄油,以及MedDiet中食用频率较低的三种食物:红肉、家禽和全脂乳制品,使用经验证的问卷来评估对MedDiet的依从性。进行二元逻辑回归,将认知功能作为因变量MedDiet依从性得分,并将双变量分析中与CI相关的食物消耗频率作为自变量。对混杂变量进行调整后的二元逻辑回归显示,坚持MedDiet与认知障碍风险的降低无关(ORa=0.928;95%CI;[0.831-1.037])(ORa:调整后的比值比;95%CI:95%置信区间)。然而,只有食用橄榄油是预防CI的保护因素(ORa=0.882;95%CI;[0.815-0.953])。