A Case of Oculomotor Nerve Paralysis Caused by Cavernous Sinus Metastasis of Tonsil Cancer.

Journal of Rhinology Pub Date : 2022-03-01 Epub Date: 2022-02-11 DOI:10.18787/jr.2021.00381
Younghac Kim, Man Ki Chung, Sang Duk Hong
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Abstract

Oropharyngeal squamous cell carcinoma (OSCC) with metastasis to the cavernous sinus (CS) is uncommon, and only a few cases have been described in the literature. The highest age-adjusted incidence rate for OSCC including the tonsil in males occurs in South Asians, and more cases should be reported to establish earlier identification and treatment. We report a case of OSCC in a 59-year-old male who underwent prompt endoscopic biopsy and early palliative radiation therapy to allow complete recovery of cranial nerve palsies to improve his quality of life, despite having a poor prognosis. Furthermore, this report emphasizes his dramatic resolution of symptoms after radiation therapy, highlighting the importance of rapid recognition and proper management.

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扁桃体癌海绵窦转移致动眼神经麻痹1例
扁桃体癌症的发病率一直在增加,这可归因于与人乳头瘤病毒(HPV)感染相关的诊断比例不断增加[1]。因为HPV阳性的口咽鳞状细胞癌(OSCC)比HPV阴性的OSCC对放化疗更敏感[2]。与没有HPV感染的情况相比,HPV阳性OSCC的病例与更有利的结果相关[3]。15%至20%的口咽癌发生远处转移,最常见的转移部位是肺、肝和骨,一些回顾性综述报道,与HPV相关疾病的转移更有可能包括不寻常的部位[4]。由于海绵窦涉及颅神经III至VI,海绵窦转移患者可能表现出急性发作性复视、上睑下垂和麻痹性斜视的症状。以前很少有作者报道头部和颈部癌症转移到海绵窦,尤其是很少有亚洲病例报道。我们报告了一名由海绵窦转移引起的复视、上睑下垂和麻痹性斜视患者,该患者先前被诊断为HPV阳性OSCC。
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发文量
23
审稿时长
8 weeks
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