Role of the lung function test in asthmatic children admitted to Al-Azhar University (Assiut)

A. Hamed, M. Mohammed, K. Awad, Y. Abdel-Rahman
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Abstract

Background and aim Lung function, especially spirometry, is an important investigatory tool in the evaluation of asthma in children. This study aimed to compare the clinical condition of asthmatic children using the lung function test before and after treatment and after 3 months as a follow-up of asthmatic patients admitted to Al-Azhar Assiut University Hospital. Patients and methods This clinical study was a prospective study that included 60 asthmatic children aged 6–16 years with bronchial asthma plus 30 children matched for age, sex and nutritional status as a control group over a period of 13 months from December 1, 2019 to December 31, 2020. Results The age of the children included in this study was found to be mean±SD 9.033±2.843, with a male predominance (male : female ratio 58% : 42%) and a positive family history of asthma (61%) and other allergic disorders (65%). There was a statistically significant change in forced expiratory volume at first second (FEV1), forced vital capacity (FVC), and the FEV1/FVC ratio that showed considerable improvement in both age groups at admission, after receiving the suitable treatment and at follow-up 3 months after discharge. Conclusion Pediatric asthma is a major clinical concern and represents a huge burden on the family and society, hence the importance of prompt and early diagnosis that includes lung function testing, especially FEV1, FVC, and FEV1/FVC ratio, in not only diagnosis but also for monitoring the efficacy of treatment and follow-up.
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肺功能检查在爱资哈尔大学(Assiut)哮喘患儿中的作用
背景与目的肺功能,尤其是肺活量测定是评估儿童哮喘的重要调查工具。本研究旨在比较哮喘患儿治疗前后及随访3个月后肺功能检查的临床情况,作为对爱资哈尔阿西尤特大学医院哮喘患儿的随访。患者与方法本临床研究是一项前瞻性研究,于2019年12月1日至2020年12月31日为期13个月,纳入60名6-16岁支气管哮喘患儿和30名年龄、性别和营养状况匹配的儿童作为对照组。结果本组患儿年龄均值±SD为9.033±2.843,男性为主(男女比例58%:42%),有哮喘家族史(61%)和其他过敏性疾病家族史(65%)。两组患者入院时、接受适当治疗后及出院后3个月随访时第一秒用力呼气量(FEV1)、用力肺活量(FVC)、FEV1/FVC比值均有显著改善,差异均有统计学意义。结论儿童哮喘是临床关注的主要问题,给家庭和社会带来了巨大的负担,因此及时早期诊断,包括肺功能检测,特别是FEV1、FVC、FEV1/FVC比值,不仅对诊断有重要意义,对监测治疗效果和随访也有重要意义。
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审稿时长
34 weeks
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