{"title":"Log-symmetric models with cure fraction with application to leprosy reactions data","authors":"J. B. Rocha, F. Medeiros, Dione M. Valencca","doi":"10.1214/22-bjps540","DOIUrl":null,"url":null,"abstract":"In this paper, we propose a log-symmetric survival model with cure fraction, considering that the distributions of lifetimes for susceptible individuals belong to the log-symmetric class of distributions. This class has continuous, strictly positive, and asymmetric distributions, including the log-normal, log-$t$-Student, Birnbaum-Saunders, log-logistic I, log-logistic II, log-normal-contaminated, log-exponential-power, and log-slash distributions. The log-symmetric class is quite flexible and allows for including bimodal distributions and outliers. This includes explanatory variables through the parameter associated with the cure fraction. We evaluate the performance of the proposed model through extensive simulation studies and consider a real data application to evaluate the effect of factors on the immunity to leprosy reactions in patients with Hansen's disease.","PeriodicalId":51242,"journal":{"name":"Brazilian Journal of Probability and Statistics","volume":null,"pages":null},"PeriodicalIF":0.6000,"publicationDate":"2021-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brazilian Journal of Probability and Statistics","FirstCategoryId":"100","ListUrlMain":"https://doi.org/10.1214/22-bjps540","RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"STATISTICS & PROBABILITY","Score":null,"Total":0}
引用次数: 0
Abstract
In this paper, we propose a log-symmetric survival model with cure fraction, considering that the distributions of lifetimes for susceptible individuals belong to the log-symmetric class of distributions. This class has continuous, strictly positive, and asymmetric distributions, including the log-normal, log-$t$-Student, Birnbaum-Saunders, log-logistic I, log-logistic II, log-normal-contaminated, log-exponential-power, and log-slash distributions. The log-symmetric class is quite flexible and allows for including bimodal distributions and outliers. This includes explanatory variables through the parameter associated with the cure fraction. We evaluate the performance of the proposed model through extensive simulation studies and consider a real data application to evaluate the effect of factors on the immunity to leprosy reactions in patients with Hansen's disease.
期刊介绍:
The Brazilian Journal of Probability and Statistics aims to publish high quality research papers in applied probability, applied statistics, computational statistics, mathematical statistics, probability theory and stochastic processes.
More specifically, the following types of contributions will be considered:
(i) Original articles dealing with methodological developments, comparison of competing techniques or their computational aspects.
(ii) Original articles developing theoretical results.
(iii) Articles that contain novel applications of existing methodologies to practical problems. For these papers the focus is in the importance and originality of the applied problem, as well as, applications of the best available methodologies to solve it.
(iv) Survey articles containing a thorough coverage of topics of broad interest to probability and statistics. The journal will occasionally publish book reviews, invited papers and essays on the teaching of statistics.