Two Rare Mechanisms for Acute Anuric Renal Failure in a Patient with Metastatic Malignant Melanoma - A Case Report

Kennedy Amy D, Liu Alex J, Seipp Regan M, Ryan Margaret S, Yang Shaun K, Thomas Leslie F
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Abstract

This case report examines two rare mechanisms of acute renal failure in a patient with metastatic melanoma treated with high-dose vitamin C. The first is oxalate nephropathy, which is an uncommon but known complication of highdose vitamin C therapy in naturopathic medicine. The second is due to melanuria and renal melanosis, which has been described in metastatic melanoma; however, acute renal failure requiring renal replacement therapy has not been reported previously.
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转移性恶性黑色素瘤患者急性无尿肾功能衰竭的两种罕见机制——一例报告
本病例报告探讨了接受高剂量维生素C治疗的转移性黑色素瘤患者急性肾功能衰竭的两种罕见机制。第一种是草酸肾病,这是自然疗法中高剂量维生素C治疗的一种罕见但已知的并发症。第二种是由于黑色素瘤和肾黑素病,这在转移性黑色素瘤中有描述;然而,需要肾脏替代治疗的急性肾功能衰竭以前没有报道。
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