A rare case of urosepsis caused by multidrug-resistant Escherichia hermannii in an immunocompetent toddler

IF 0.2 Q4 UROLOGY & NEPHROLOGY Journal of Renal Injury Prevention Pub Date : 2023-02-25 DOI:10.34172/jrip.2023.32077
Roham Sarmadian, P. Yousefichaijan, M. Kahbazi
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Abstract

Escherichia hermannii is a gram-negative bacillus from the Enterobacteriaceae family. The formation of a yellow pigment distinguishes E. hermannii from Escherichia coli in the laboratory. This organism is a rare cause of invasive infections, initially thought to be a colonizer microbe with low- pathogenicity. Our report discusses a case of urosepsis caused by E. hermannii in a 17-month-old female patient with a complaint of fever and irritability and also a history of urinary tract infection (UTI) with nephrolithiasis. The isolated bacterium from urine and blood cultures was multidrug-resistant E. hermannii. The patient’s symptoms were improved after treatment with cotrimoxazole and imipenem. This case provides evidence that E. hermannii can be pathogenic and infect the urinary tract. Moreover, the bacterium isolated from this patient indicates that more resistant E. hermannii strains are forming.
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一例罕见的尿脓毒症引起多药耐药赫氏埃希菌在一个免疫能力的幼儿
赫曼氏埃希氏杆菌是肠杆菌科的一种革兰氏阴性杆菌。在实验室中,一种黄色色素的形成将赫曼氏大肠杆菌与大肠杆菌区分开来。这种生物是一种罕见的侵袭性感染原因,最初被认为是一种低致病性的定植微生物。我们的报告讨论了一例由E.hermanii引起的尿路败血症,该病例发生在一名17个月大的女性患者身上,她有发烧和易怒的主诉,也有尿路感染(UTI)伴肾结石的病史。从尿液和血液培养物中分离出的细菌是耐多药的埃曼氏大肠杆菌。患者的症状在使用复方新诺明和亚胺培南治疗后得到改善。这个病例提供了证据,证明E.hermannii可以致病并感染尿路。此外,从该患者身上分离出的细菌表明,正在形成更具耐药性的埃曼氏大肠杆菌菌株。
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来源期刊
Journal of Renal Injury Prevention
Journal of Renal Injury Prevention UROLOGY & NEPHROLOGY-
CiteScore
1.60
自引率
0.00%
发文量
36
期刊介绍: The Journal of Renal Injury Prevention (JRIP) is a quarterly peer-reviewed international journal devoted to the promotion of early diagnosis and prevention of renal diseases. It publishes in March, June, September and December of each year. It has pursued this aim through publishing editorials, original research articles, reviews, mini-reviews, commentaries, letters to the editor, hypothesis, case reports, epidemiology and prevention, news and views and renal biopsy teaching point. In this journal, particular emphasis is given to research, both experimental and clinical, aimed at protection/prevention of renal failure and modalities in the treatment of diabetic nephropathy. A further aim of this journal is to emphasize and strengthen the link between renal pathologists/nephropathologists and nephrologists. In addition, JRIP welcomes basic biomedical as well as pharmaceutical scientific research applied to clinical nephrology. Futuristic conceptual hypothesis that integrate various fields of acute kidney injury and renal tubular cell protection are encouraged to be submitted.
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