Unusual in Water Multicomponent Reaction of 3-Amino-5-methylpyrazole, Acetylacetone and Aldehyde

IF 0.4 Q4 CHEMISTRY, ANALYTICAL French-Ukrainian Journal of Chemistry Pub Date : 2019-07-30 DOI:10.17721/FUJCV7I1P90-95
I. G. Tkachenko, S. A. Komykhov, V. Musatov, V. Chebanov, S. Desenko
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引用次数: 1

Abstract

Multicomponent reaction of 3-amino-5-methylpyrazole, aliphatic aldehyde (paraformaldehyde or acetaldehyde) and acetylacetone in water by conventional heating, microwave or ultrasound activation undergoes on molar amounts of reagents 2:1:2, respectively, leads bis(2,5,7-trimethylpyrazolo[1,5-a]pyrimidin-6-yl)-substituted methane or to corresponding 1,1-bis-substituted ethane.
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3-氨基-5-甲基吡唑、乙酰丙酮和醛在水中多组分反应中的罕见现象
3-氨基-5-甲基吡唑、脂肪醛(多聚甲醛或乙醛)和乙酰丙酮在水中经常规加热、微波或超声活化,分别按摩尔量2:1:2进行多组分反应,得到二(2,5,7-三甲基吡唑[1,5-a]嘧啶-6-基)取代甲烷或相应的1,1-二取代乙烷。
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来源期刊
French-Ukrainian Journal of Chemistry
French-Ukrainian Journal of Chemistry CHEMISTRY, ANALYTICAL-
自引率
0.00%
发文量
13
审稿时长
4 weeks
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