Maternal Prenatal Anthropometry, High Education and Cesarean Delivery as Risk Factors for Low Gestational Age in Iran

S. Kheirouri, M. Alizadeh, P. Sarbakhsh
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Abstract

Preterm birth is an important contributor to the global burden of disease. Evidence indicating that maternal health, nutritional and socioeconomic status may contribute to preterm birth. This cross-sectional study was conducted to describe the contribution of prenatal maternal factors on low gestational age, and to assess newborns anthropometric measurements regarding gestational age. Data of mothers delivering a singleton live infant (n= 759) and their newborns (n= 755) during the two years up to August 2014 were collected. Data were collected from the data set of eight public health centers which were chosen from different administrative regions of Tabriz city and were analyzed. Differences between the groups were assessed by Student’s t-test or one- way analysis of variance (ANOVA). Multiple linear regression was used to estimate the association between gestational age and variables studied. Incidence of preterm birth was 2.1%. Percentage of infants with low birth weight and Head Circumference (HC) under 34 cm was significantly higher in the preterm group. Mean gestational age was lower in mothers with cesarean delivery, high education, high economic status, high BMI, pre-pregnancy weight ≥ 65 kg and medical problem. Gestational age was inversely associated with maternal pre-pregnancy weight ≥ 65 kg (B= -0.20, p= 0.02), high BMI (B= -0.33, p= 0.01), high education (B= -0.47, p= 0.002) and cesarean delivery (B= -0.74, p< 0.001). The results indicate that maternal anthropometric characteristics, education and type of delivery are associated with gestational age. Explorating potentially modifiable risk factors for unfavorable gestational age and integrating them into intervention efforts may ameliorate adverse birth outcomes.
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母亲产前人体测量、高教育程度和剖宫产是伊朗低孕龄的危险因素
早产是造成全球疾病负担的一个重要因素。有证据表明,产妇的健康、营养和社会经济地位可能导致早产。本横断面研究旨在描述产前母体因素对低胎龄的影响,并评估新生儿胎龄的人体测量值。收集截至2014年8月的两年内分娩单胎活婴(n= 759)的母亲及其新生儿(n= 755)的数据。从大不里士市不同行政区域的八个公共卫生中心的数据集中收集数据并进行分析。采用学生t检验或单因素方差分析(ANOVA)评估组间差异。使用多元线性回归来估计胎龄与研究变量之间的关系。早产发生率为2.1%。早产儿组低出生体重和头围(HC)小于34 cm的婴儿比例明显高于早产儿组。剖宫产、高学历、高经济地位、高BMI、孕前体重≥65 kg和有医疗问题的母亲平均胎龄较低。胎龄与产妇孕前体重≥65 kg (B= -0.20, p= 0.02)、高BMI (B= -0.33, p= 0.01)、高学历(B= -0.47, p= 0.002)、剖宫产(B= -0.74, p< 0.001)呈负相关。结果表明,产妇的人体测量特征、教育程度和分娩类型与胎龄有关。探索不利胎龄的潜在可改变的危险因素,并将其纳入干预措施,可能会改善不良分娩结果。
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