Pu-Fan Qian, Jun-Yi Li, Yi-Bo Zhou, Tao Zhou, Bing‐Feng Shi
{"title":"Half-Sandwich d 6 -Metal (Co III , Rh III , Ir III , Ru II )-Catalyzed Enantioselective C–H Activation","authors":"Pu-Fan Qian, Jun-Yi Li, Yi-Bo Zhou, Tao Zhou, Bing‐Feng Shi","doi":"10.1055/a-2167-8298","DOIUrl":null,"url":null,"abstract":"Transition metal-catalyzed enantioselective C–H activation has provided a straightforward strategy to synthesize chiral molecules from readily available sources. In this graphic review, we summarized the progress of half-sandwich d6 metal (CoIII, RhIII, IrIII, RuII) catalyzed enantioselective C–H functionalization reactions. The review was categorized according to the types of metal catalysts and chiral ligands. Representative enantio-determining models and catalytic cycles were presented. We hope this graphic review would stimulate further efforts on the development of novel chiral ligands and strategies in this emerging research topic.","PeriodicalId":22135,"journal":{"name":"SynOpen","volume":"07 1","pages":"466 - 485"},"PeriodicalIF":2.0000,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"SynOpen","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/a-2167-8298","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
Transition metal-catalyzed enantioselective C–H activation has provided a straightforward strategy to synthesize chiral molecules from readily available sources. In this graphic review, we summarized the progress of half-sandwich d6 metal (CoIII, RhIII, IrIII, RuII) catalyzed enantioselective C–H functionalization reactions. The review was categorized according to the types of metal catalysts and chiral ligands. Representative enantio-determining models and catalytic cycles were presented. We hope this graphic review would stimulate further efforts on the development of novel chiral ligands and strategies in this emerging research topic.