Comparison of Montreal Cognitive Assessment (MOCA) with Mini Mental State Examination (MMSE) on association between homocysteine and cognitive status in epilepsy patients with phenytoin monotherapy
Rajendran Natham, P. Amirthalingam, Ganesvaran Arunachalam
{"title":"Comparison of Montreal Cognitive Assessment (MOCA) with Mini Mental State Examination (MMSE) on association between homocysteine and cognitive status in epilepsy patients with phenytoin monotherapy","authors":"Rajendran Natham, P. Amirthalingam, Ganesvaran Arunachalam","doi":"10.1080/21507686.2018.1483411","DOIUrl":null,"url":null,"abstract":"ABSTRACT Mini Mental State Examination (MMSE) has been used as a tool to detect cognitive impairment in patients treated with antiepileptic drugs, however fail to detect mild cognitive impairment in these patients. Studies report Montreal Cognitive Assessment (MOCA) is more sensitive than MMSE in detecting cognitive status in patients with stroke, parkinsonism, cardiovascular disease and epilepsy. Homocysteine has been implicated in the modulation of cognitive impairment in epilepsy but could not be established clearly as most studies followed MMSE. To investigate the relationship between homocysteine and cognitive status the present study employed MOCA in comparison with MMSE in epilepsy population with phenytoin monotherapy. Our findings suggest MOCA is more sensitive than MMSE in demonstrating the relationship between homocysteine and cognitive impairment in epilepsy.","PeriodicalId":0,"journal":{"name":"","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/21507686.2018.1483411","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"","FirstCategoryId":"102","ListUrlMain":"https://doi.org/10.1080/21507686.2018.1483411","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
ABSTRACT Mini Mental State Examination (MMSE) has been used as a tool to detect cognitive impairment in patients treated with antiepileptic drugs, however fail to detect mild cognitive impairment in these patients. Studies report Montreal Cognitive Assessment (MOCA) is more sensitive than MMSE in detecting cognitive status in patients with stroke, parkinsonism, cardiovascular disease and epilepsy. Homocysteine has been implicated in the modulation of cognitive impairment in epilepsy but could not be established clearly as most studies followed MMSE. To investigate the relationship between homocysteine and cognitive status the present study employed MOCA in comparison with MMSE in epilepsy population with phenytoin monotherapy. Our findings suggest MOCA is more sensitive than MMSE in demonstrating the relationship between homocysteine and cognitive impairment in epilepsy.
分享
京公网安备 11010802042870号
京ICP备2023020795号-1
求助内容：
应助结果提醒方式：
扫码关注我们
