Intralesional corticosteroid injections as first option for management of giant cell lesion of the lower jaw in a 56-year-old patient: A case report and brief literature review

Abstract

Giant cell lesions of the maxillofacial region constitute a diverse group of lesions, which frequently affect the lower jaw, and are commonly detected at younger ages, in the second and third decades of life. They can be categorized as aggressive or non-aggressive lesions, mainly based on clinical behavior. Management is most commonly through surgical intervention. However, many patients consider surgery to be unfavorable due to the sacrifice of surrounding anatomic structures, potentially necessitating reconstruction procedures. Therefore, alternative modalities of conservative therapy have emerged. One method of alternative management is intralesional corticosteroid injections, which have been described with promising results. Here we report our experience with the treatment of a 56-year-old female patient, in whom a non-aggressive giant cell lesion was managed using intralesional steroid injections. This treatment resulted in total regression according to radiographic examinations.