{"title":"Pituitary stalk interruption syndrome in newborn: a case report","authors":"Hui-ping Shi, L. Tao, Ning Zhao","doi":"10.3760/CMA.J.ISSN.1007-9408.2019.12.010","DOIUrl":null,"url":null,"abstract":"This study reported a postterm female infant born at 43+2 weeks of gestation via cesarean section with a birth weight of 2 950 g. Cyanosis was presented around 14 h after birth. Laboratory test results showed that the blood glucose was 1.4 mmol/L and the levels of free triiodothyronine (FT3), free tetraiodothyronine (FT4), thyrotropin (TSH), growth hormone (GH) and insulin-like growth factor-1 (IGF-1) were significantly reduced. Cranial MRI confirmed the diagnosis of pituitary stalk interruption syndrome. The baby girl was treated with hydrocortisone and levothyroxine and discharged following clinical symptoms improvement and blood glucose normalization. Follow-up data showed unstable blood glucose and hypothyroidism at six and 10 months after birth and growth retardation at 15 months. \n \n \nKey words: \nPituitary diseases; Hypoglycemia; Hypothyroidism; Infant, newborn","PeriodicalId":52320,"journal":{"name":"中华围产医学杂志","volume":"22 1","pages":"891-893"},"PeriodicalIF":0.0000,"publicationDate":"2019-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华围产医学杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1007-9408.2019.12.010","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
This study reported a postterm female infant born at 43+2 weeks of gestation via cesarean section with a birth weight of 2 950 g. Cyanosis was presented around 14 h after birth. Laboratory test results showed that the blood glucose was 1.4 mmol/L and the levels of free triiodothyronine (FT3), free tetraiodothyronine (FT4), thyrotropin (TSH), growth hormone (GH) and insulin-like growth factor-1 (IGF-1) were significantly reduced. Cranial MRI confirmed the diagnosis of pituitary stalk interruption syndrome. The baby girl was treated with hydrocortisone and levothyroxine and discharged following clinical symptoms improvement and blood glucose normalization. Follow-up data showed unstable blood glucose and hypothyroidism at six and 10 months after birth and growth retardation at 15 months.
Key words:
Pituitary diseases; Hypoglycemia; Hypothyroidism; Infant, newborn
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