Candida glabrata Infection: A Rare Complication of Chest Trauma

Olugbemi Aj, Thomas F. Mo, Ogunleye Eo, Olusoji Oo, Ojo Oo, Sanni Sb
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Abstract

Candida species are fungi, which are ubiquitous organisms. It is a normal flora of the oral cavity, genitourinary and gastrointestinal tract. An increasing incidence of fungal infections with Candida species has been noted in immunocompromised patients such as intensive care, postsurgical, and neutropenic patients. Candida species are detected in approximately 31 to 55% of healthy individuals. They are more common in immunocompromised individuals. Colonization rates increase with severity of illness and duration of hospitalization. We present a 32-year-old male who presented at our institution with a thoracoabdominal penetrating injury following assault. He had injury to the stomach and left hemi diaphragm, with moderate hemothorax. He had surgery done with repair of the stomach and diaphragm. He however developed chest infection with empyma thoracis thereafter. Culture of the pleural effluent revealed growth of Canddida glabrata which was sensitive to Ketoconazole. He was treated for two weeks and subsequently discharged from the ward and followed up in the clinic. Though C. glabrata infection of the chest is rare, it is however useful to exclude fungal infection in patients with empyema thoracic, as early diagnosis and treatment provides good outcome.
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光滑念珠菌感染:一种罕见的胸部创伤并发症
念珠菌是真菌,是普遍存在的生物体。它是口腔、泌尿生殖道和胃肠道的正常菌群。免疫功能低下的患者,如重症监护、术后和中性粒细胞减少的患者,念珠菌感染的发生率越来越高。在大约31%至55%的健康个体中检测到念珠菌。它们在免疫功能受损的个体中更常见。殖民化率随着疾病的严重程度和住院时间的延长而增加。我们报告了一名32岁的男性,他在我们的机构就诊时遭受了袭击后的胸腹穿透性损伤。他的胃和左半横膈膜受伤,有中度血胸。他做了胃和横膈膜修复手术。然而,他后来患上了胸部感染和胸腔积液。胸膜流出物的培养显示了对酮康唑敏感的光滑Canddida glabrata的生长。他接受了两周的治疗,随后出院并在诊所接受了随访。尽管胸部光滑乳杆菌感染很罕见,但排除胸部脓胸患者的真菌感染是有用的,因为早期诊断和治疗可以提供良好的结果。
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