Placental development and its control in cattle

Jan-Dirk Haeger, N. Hambruch, C. Pfarrer
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引用次数: 4

Abstract

This review aims to provide an overview of the current knowledge regarding the development and function of the bovine placenta, starting with the gross anatomical morphology and histology. In addition, detailed information on trophoblast giant cell formation (TGC) and the complex interplay of the extracellular matrix (ECM) proteins, integrins and growth factor systems is given. Drugs and pathological conditions (e.g. cloned placenta, retained placenta) are also reviewed. Knowledge derived from cell culture studies is embedded and set in proportion to the data gained from in vivo experiments. Finally, new discoveries and the major challenges for future work on the bovine placenta close the circle, in order to provide a complete picture of what is known about this fascinating, synepitheliochorial organ.
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牛胎盘发育及其控制
本文综述了目前关于牛胎盘发育和功能的知识,从大体解剖形态和组织学开始。此外,还详细介绍了滋养层巨细胞形成(TGC)和细胞外基质(ECM)蛋白、整合素和生长因子系统的复杂相互作用。药物和病理情况(如克隆胎盘,保留胎盘)也进行了审查。从细胞培养研究中获得的知识被嵌入并与体内实验获得的数据成比例。最后,关于牛胎盘的新发现和未来工作的主要挑战闭合了这个循环,以便提供一个关于这个迷人的,联神经器官的完整图景。
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