Determination of Hemobiochemical Profiles of Apparently Healthy Exotic Breed of Dogs in Jos, Plateau State, Nigeria

K. Ogbu, K. Ezema, Ijeoma C. Adieme, R. I. Malgwi, Jibreel A. Sabo, Philip N. Ayuba, Samuel A. Nguety, Simone T. Atuna, Francis O. Emeribe, J. Shallmizhili, B. Anene
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Abstract

The hematological and serum biochemical profiles of apparently healthy exotic breed of dogs in Jos, Plateau state, Nigeria was studied in this research. One hundred and seven exotic breed of dogs were examined from October - December, 2018. The results from physical, clinical examinations and parasitological examinations were used to determine apparently healthy exotic breed of dogs which were used in this study. The parameters measured were rectal temperature, parasitaemia, hematology which included red blood cells count, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin and hemoglobin content; total white blood cell count, including eosinophils, neutrophils, lymphocytes, monocytes, granulocytes counts, and platelets; serum biochemical parameters also included Aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, total proteins, albumin, globulin, blood urea nitrogen, creatinine, cholesterol and triglyceride, using standard methods. Data generated from the study were statistically analyzed using students t-test one-way analysis of variance while the level of significance was measured at p < 0.05. From this study, hematological and serum biochemical values were comparable to and not different from those reported for dogs in available literature, but the upper and lower reference limits (minimum and maximum values) were different for most parameters. Sex-related significant difference (p < 0.05) occurred only in WBC and total protein while age-related significant difference occurred only in total protein and urea level. Breed affected the MCHC and total bilirubin level which was evident in higher MCHC level in Neapolitan mastiff than Alsatian breed while total bilirubin was higher in Alsatian breed than Bull mastiff (p < 0.05). The present study has presented preliminary information on the range of hematological and serum biochemistry profile of exotic breed of dogs in Jos, Plateau state, Nigeria which may be useful to biomedical researchers and veterinary clinicians.
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尼日利亚高原州乔斯市明显健康的外来犬种血液生化图谱的测定
本研究对尼日利亚高原州乔斯地区明显健康的外来犬种的血液学和血清生化特征进行了研究。从2018年10月至12月,对107只外来品种的狗进行了检查。采用体格检查、临床检查和寄生虫学检查的结果来确定本研究所用的外来犬种表面健康。测量的参数包括直肠温度、寄生虫血症、血液学指标,包括红细胞计数、红细胞比容、平均红细胞体积、平均红细胞血红蛋白、平均红细胞血红蛋白和血红蛋白含量;白细胞总数,包括嗜酸性粒细胞、中性粒细胞、淋巴细胞、单核细胞、粒细胞计数和血小板计数;血清生化指标:天门冬氨酸转氨酶、丙氨酸转氨酶、碱性磷酸酶、总蛋白、白蛋白、球蛋白、血尿素氮、肌酐、胆固醇、甘油三酯,采用标准方法测定。本研究产生的数据采用学生t检验单因素方差分析进行统计学分析,p < 0.05为显著性水平。从本研究中,血液学和血清生化值与现有文献中报道的狗的血液学和血清生化值相当,但大多数参数的上下限(最小值和最大值)不同。白细胞和总蛋白存在性别相关差异(p < 0.05),总蛋白和尿素存在年龄相关差异(p < 0.05)。品种影响MCHC和总胆红素水平,其中那不勒斯獒的MCHC水平高于阿尔萨斯獒,阿尔萨斯獒的总胆红素水平高于公牛獒(p < 0.05)。本研究提供了尼日利亚乔斯高原州外来犬种血液学和血清生化特征范围的初步信息,可能对生物医学研究人员和兽医临床医生有用。
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