Antibiotic Susceptibility Of Klebsiella pneumoniae Strains Isolated From Clinical Samples

Abstract

Antibiotic resistance in bacteria has become a worrying phenomenon in today's world. K. pneumoniae is a member of the Enterobacteriaceae family, which causes nosocomial infections as an opportunistic pathogen but inherently harboured as a part of natural human microbiota. Carbapenem resistance of K. pneumoniae was a rare occurrence up to ten years ago, but in recent years many types of carbapenemase producing K. pneumoniae have become common. The aim of this retrospective study; analyzing susceptibility to various antibiotics, commonly used in treatment, against K. pneumoniae strains isolated from various infection sites. Antibiotic susceptibility tests were performed by using the VITEK 2 Compact ® automated system. In this study, 502 K. pneumoniae strains  isolated from patients that treated at various services of a university hospital with 515 bed capacity were examined. When compared to the data available with studies of recent years in Turkey, especially in intensive care and inpatient services, resistance of K. pneumoniae strains to antibiotics, against most carbapenems, are rapidly increasing in the degree of high concern. Therefore, in all hospitals, antibiotic management policies should be implemented with a multidisciplinary approach.