Why are there so Many non-coding DNAs with Repeating Sequences of Nucleotides in the Genome of Higher Eukaryotes?

Abstract

There are many questions regarding the biological roles of non-coding DNAs (ncDNAs) in the eukaryotic genome. It is noteworthy that ncDNAs, despite the overwhelming majority in the genome is still a mysterious object. From simple theoretical considerations, it follows that this vast class of ncDNAs should play some important role in the vital activity of higher eukaryotes. If by their nature they are not capable create specific biological products (proteins, enzymes or RNAs), then they must form some non-specific structures in the cell that are important in the vital activity of higher eukaryotes. Thus, from our point of view, excess ncDNAs were fixed in the genome of higher eukaryotes mainly due to the presence in their composition of sites with repetitive sequences of nucleotides and their wide variability in the population, which ultimately played a decisive role in the emergence of the eukaryotic nucleus and cells, biological sex and species, large multicellular and warm-blooded organisms, up to modern humans.