G. Paas, Jeremy Owen G. Go, Ezekiel Morena S. Rivera, Margarita Ysabel S. Mangahas, Eunice Marie Perez-Trajano, Raul D. Jara
{"title":"Beta-3 Adrenoreceptor: Boon or Bane in Heart Failure?","authors":"G. Paas, Jeremy Owen G. Go, Ezekiel Morena S. Rivera, Margarita Ysabel S. Mangahas, Eunice Marie Perez-Trajano, Raul D. Jara","doi":"10.33425/2639-8486.1079","DOIUrl":null,"url":null,"abstract":"Inclusion criteria We included published studies on humans, review articles, and experimental studies in human tissues published in PubMed, MEDLINE, Herdin, and Cochrane which discussed the effects ABSTRACT Background: In a recent publication, four beta blockers—Metoprolol, Carvedilol, Bisoprolol, and Nebivolol have shown good effects in heart failure. Published studies on the role of beta-3 receptor (B3AR) agonism over the past 3 decades had conflicting results. Recent experimental studies described its role in coupling mechanisms with nitric oxide, offering protection in damaged cardiac myocytes.","PeriodicalId":72522,"journal":{"name":"Cardiology & vascular research (Wilmington, Del.)","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cardiology & vascular research (Wilmington, Del.)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33425/2639-8486.1079","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Inclusion criteria We included published studies on humans, review articles, and experimental studies in human tissues published in PubMed, MEDLINE, Herdin, and Cochrane which discussed the effects ABSTRACT Background: In a recent publication, four beta blockers—Metoprolol, Carvedilol, Bisoprolol, and Nebivolol have shown good effects in heart failure. Published studies on the role of beta-3 receptor (B3AR) agonism over the past 3 decades had conflicting results. Recent experimental studies described its role in coupling mechanisms with nitric oxide, offering protection in damaged cardiac myocytes.
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